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Effects of zonisamide on tardive dyskinesia: a preliminary open-label trial.

Author: IrieSachiko, IwashitaSatoru, IwataYusuke, MimuraMasaru, SuzukiTakefumi, UchidaHiroyuki, WatanabeKoichiro

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Tardive dyskinesia (TD) is a challenging condition to treat. This study examined the efficacy, tolerability, and safety of zonisamide, an antiepileptic drug, for the treatment of TD in psychiatric patients.
Paper Details　
Original Abstract of the Article :
Once developed, tardive dyskinesia (TD) is a challenging condition to treat. The recent evidence has indicated that zonisamide, an antiepileptic drug indicated for partial-onset seizures, may also have beneficial effects for ameliorating dyskinesia in Parkinson's disease. However, this finding has n...See full text at original site
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引用元：
https://doi.org/10.1016/j.jns.2011.12.010

データ提供：米国国立医学図書館（NLM）

Zonisamide: A Potential Treatment for Tardive Dyskinesia

Tardive dyskinesia (TD) is a movement disorder that can be a challenging condition to treat. This study investigates the potential of zonisamide, an antiepileptic drug, in managing TD in patients who have developed this condition as a side effect of antipsychotic treatment. The researchers conducted a preliminary open-label trial to evaluate the efficacy and tolerability of zonisamide for TD.

Zonisamide: A Potential Therapeutic Option for Tardive Dyskinesia

The study found that zonisamide was well-tolerated and showed promise in reducing TD symptoms. A significant decrease in the severity of TD was observed in the study participants, suggesting that zonisamide may be a potential therapeutic option for TD. However, further research with larger sample sizes is needed to confirm these findings.

Finding Relief from Tardive Dyskinesia: Exploring New Treatment Options

This research offers a glimmer of hope for patients struggling with TD by exploring the potential of zonisamide as a treatment option. It's like finding a hidden spring in the desert of TD research – a source of potential therapeutic strategies that could bring relief to patients.

Dr. Camel's Conclusion

This study is a reminder that the search for effective treatments for complex conditions like TD is an ongoing journey. Just as a camel can adapt to the harsh desert environment, researchers are constantly seeking new and innovative approaches to improve patient care. The findings regarding zonisamide offer a promising lead, but further research is needed to fully understand its potential and to develop the best possible treatments for TD.

Date :
  1. Date Completed 2012-11-20
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

22285275

DOI: Digital Object Identifier

10.1016/j.jns.2011.12.010

Related Literature

Article Analysis
・Effects of zonisamide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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