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Overall benefit of antiretroviral treatment on the risk of fracture in HIV: nested case-control analysis in a health-insured population.
Author: BowlinSteve J, McComseyGrace A, MundyLinda M, YoukAda O
Original Abstract of the Article :
OBJECTIVES: Fractures are common and associated with multiple risk factors. We assessed the risks of fracture associated with time-dependent, differential antiretroviral drug exposures among a cohort of persons with HIV infection. DESIGN: Nested case-control study from an HIV cohort of 59,594 medic...See full text at original site
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引用元:
https://doi.org/10.1097/QAD.0b013e328351997f
データ提供:米国国立医学図書館(NLM)
Navigating the Desert of HIV Treatment and Fracture Risk
This nested case-control analysis, published in the journal Clinical Infectious Diseases, examines the association between antiretroviral therapy (ART) exposure and fracture risk in a cohort of HIV-infected individuals. The researchers found an overall reduced risk of fracture associated with ART use, but identified drug-specific differences. Some drugs, such as darunavir, delavirdine, and saquinavir, were associated with increased fracture risk, while others, such as efavirenz, emtricitabine, lamivudine, tenofovir, and zidovudine, were associated with reduced fracture risk. This study, like a camel navigating a complex desert landscape, reveals the multifaceted nature of HIV treatment and its impact on bone health.
Understanding the Impact of ART on Bone Health
This research highlights the importance of considering bone health in the context of HIV treatment. The study's findings demonstrate that ART can have both positive and negative impacts on fracture risk, depending on the specific drugs used. This research, like a compass guiding a traveler through the desert, helps us navigate the complex terrain of HIV treatment with greater awareness and understanding.
Protecting Bone Health in the Journey with HIV
The study's findings underscore the need for careful monitoring of bone health in HIV-infected individuals on ART. By understanding the potential risks and benefits of different ART regimens, we can develop more effective strategies for preventing fractures and maintaining bone health in this vulnerable population. This research, like a refreshing oasis in the desert, offers a valuable resource for improving the health and well-being of individuals living with HIV.
Dr.Camel's Conclusion
This nested case-control analysis provides valuable insights into the association between antiretroviral therapy exposure and fracture risk in a cohort of HIV-infected individuals. The study's findings emphasize the importance of considering bone health in the context of HIV treatment, highlighting the need for individualized approaches to minimize fracture risk and optimize patient outcomes.
Date :
- Date Completed 2012-09-05
- Date Revised 2022-07-16
Further Info :
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