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Advances of paclitaxel formulations based on nanosystem delivery technology.

Author: ChenQ, HanX, HeZ, LiuX, LuoC, SunJ, WangY

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This paper provides an overview of recent advances in paclitaxel formulations based on nanosystems. These nanoformulations address paclitaxel's poor aqueous solubility and reduce its toxicities while enhancing its antitumor efficacy.
Paper Details　
Original Abstract of the Article :
In this paper, an overview of recent advances of paclitaxel formulations based on nanosystems is provided. Paclitaxel is very effective in the treatment of various cancers especially ovarian and breast cancer, but it demonstrates poor aqueous solubility, which results in the difficulty challenging t...See full text at original site
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引用元：
https://doi.org/10.2174/138955712800493924

データ提供：米国国立医学図書館（NLM）

Nanotechnology: Revolutionizing Paclitaxel Delivery for Cancer Treatment

This research delves into the exciting world of [nanotechnology] and explores its application in developing innovative drug delivery systems for [oncology]. Paclitaxel, a highly effective chemotherapy drug, is often limited by its poor aqueous solubility, making it challenging to deliver to target sites in the body. This research reviews the latest advancements in nanotechnology-based formulations for paclitaxel, highlighting their potential to overcome these limitations and improve treatment outcomes. This review showcases the transformative power of nanotechnology in revolutionizing cancer therapy.

Overcoming Challenges with Paclitaxel Delivery

The review highlights the use of nanosystems, such as albumin-bound paclitaxel, polymeric micelles, and liposomes, to enhance paclitaxel's solubility and targeted delivery. These innovative formulations have shown promise in reducing toxicities associated with traditional paclitaxel formulations while simultaneously enhancing its antitumor efficacy. This research paves the way for more effective and safer cancer treatments.

A New Era of Cancer Therapy

This review underscores the profound impact of nanotechnology on cancer treatment. The development of novel paclitaxel formulations holds the potential to revolutionize cancer therapy, improving treatment outcomes and enhancing the quality of life for cancer patients. This research offers a glimpse into the future of cancer therapy, where nanotechnology plays a central role in developing more effective and targeted treatments.

Dr.Camel's Conclusion

This research, like a camel navigating a vast and ever-changing desert landscape, showcases the potential of nanotechnology to reshape the landscape of cancer treatment. By overcoming the challenges associated with traditional paclitaxel delivery, these innovative formulations offer hope for a more effective and less toxic approach to cancer therapy. This research marks a significant step forward in the quest to conquer this devastating disease, paving the way for a brighter future for cancer patients.

Date :
  1. Date Completed 2012-10-12
  2. Date Revised 2019-09-18
Further Info :

Pubmed ID

22303950

DOI: Digital Object Identifier

10.2174/138955712800493924

SNS
PICO Info
in preparation
Languages

English

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