Evaluation of the reinforcing and subjective effects of heroin in combination with dextromethorphan and quinidine.

Author: ComerSandra D, SullivanMaria A, VosburgSuzanne K

Paper Details 
Original Abstract of the Article :
OBJECTIVE: Studies have suggested that the N-methyl-D-aspartate antagonist dextromethorphan may be useful in the treatment of opioid dependence. DESIGN: This double-blinded, placebo-controlled inpatient study evaluated the effects of 0, 30, and 60 mg of dextromethorphan and quinidine (DMQ) on the r...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/22320027

データ提供:米国国立医学図書館(NLM)

Dextromethorphan: A Limited Role in Opioid Dependence

Opioid dependence is a serious public health issue, and researchers are constantly looking for effective treatments. This study investigated the effects of dextromethorphan, a common cough suppressant, on the reinforcing and subjective effects of heroin in individuals recovering from opioid dependence. The study found that dextromethorphan had limited effects on heroin's reinforcing properties, suggesting that it is unlikely to be a useful treatment for opioid dependence.

Exploring Alternatives for Opioid Dependence

This research highlights the need for continued research into effective treatment options for opioid dependence. While dextromethorphan did not demonstrate significant benefits in this study, it does provide valuable information about the potential limitations of this drug in this context.

Health Implications and Lifestyle Applications

This study emphasizes the importance of understanding the complexities of opioid dependence and the need for comprehensive treatment approaches. While dextromethorphan may not be an effective treatment for opioid dependence, it is a valuable tool for managing coughs and colds. Individuals should always consult with a healthcare professional before taking any medications.

Dr.Camel's Conclusion

This study is like a desert mirage, offering a glimmer of hope for opioid dependence but ultimately revealing a limited solution. It reminds us that the path to recovery is often complex and requires a multi-faceted approach. Just as a camel relies on its endurance and resourcefulness to navigate the harsh desert, individuals struggling with opioid dependence need unwavering support and tailored treatment plans.

Date :
  1. Date Completed 2012-02-23
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

22320027

DOI: Digital Object Identifier

NIHMS716012

Related Literature

SNS
PICO Info
in preparation
Languages

English

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