Effects of exemestane and tamoxifen on hormone levels within the Tamoxifen Exemestane Adjuvant Multicentre (TEAM) trial: results of a German substudy.

Author: BauerT, HadjiP, HasenburgA, KaukaA, KiebackD G, TamsJ

Paper Details 
Original Abstract of the Article :
AIM: The aim of this study was to compare the effects of exemestane and tamoxifen on hormone levels in postmenopausal patients with hormone receptor-positive breast cancer within a Germany substudy of the Tamoxifen Exemestane Adjuvant Multinational (TEAM) trial. METHODS: Within the TEAM trial, pati...See full text at original site
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引用元:
https://doi.org/10.3109/13697137.2011.647839

データ提供:米国国立医学図書館(NLM)

Exemestane vs Tamoxifen: A Hormonal Oasis in the Desert of Breast Cancer

Breast cancer, a prevalent disease that affects millions of women worldwide, can feel like a vast and unforgiving desert. This study examines the effects of two commonly used adjuvant therapies, exemestane and tamoxifen, on hormone levels in postmenopausal women with hormone receptor-positive breast cancer.

The researchers compared the effects of these medications on various hormone levels, including testosterone, dehydroepiandrosterone sulfate (DHEAS), sex hormone binding globulin (SHBG), follicle-stimulating hormone (FSH), and parathyroid hormone (PTH). The results revealed significant differences in the hormonal effects of the two drugs, with exemestane causing an increase in testosterone and DHEAS and a decrease in SHBG and PTH, while tamoxifen had the opposite effect.

This study underscores the importance of considering the potential hormonal effects of different treatment options for breast cancer. It is like navigating a desert with multiple paths, each with its unique hormonal landscape, requiring careful consideration of the potential impact on the body.

Hormonal Navigation in the Desert of Breast Cancer: Choosing the Right Path

The findings of this study highlight the need for individualized treatment plans based on a patient's hormonal profile and specific needs. By carefully considering the potential hormonal effects of different therapies, clinicians can make informed decisions to optimize treatment outcomes and minimize potential side effects.

The Desert of Breast Cancer: Finding Hope in Hormonal Balance

Breast cancer treatment can be a challenging journey, but understanding the hormonal landscape can help us navigate this complex terrain more effectively. By working closely with your doctor, you can find a treatment path that addresses your individual needs and minimizes potential side effects, helping you find hope and stability in the midst of this difficult experience.

Dr. Camel's Conclusion

The desert of breast cancer treatment can be a complex and ever-changing landscape. This study sheds light on the hormonal effects of different therapies, reminding us that a one-size-fits-all approach may not be the best solution. By carefully navigating the hormonal pathways, we can find a more personalized and effective approach to treatment, providing greater hope and well-being for patients facing this challenging diagnosis.

Date :
  1. Date Completed 2013-01-28
  2. Date Revised 2016-11-25
Further Info :

Pubmed ID

22321061

DOI: Digital Object Identifier

10.3109/13697137.2011.647839

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