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Possible long-term effects of γ-hydroxybutyric acid (GHB) due to neurotoxicity and overdose.

Author: BruntTibor M, McMasterMinni T B, NiesinkRaymond J M, van AmsterdamJan G C

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review examines the potential neurotoxicity of GHB, a commonly used recreational drug. While often perceived as harmless, GHB overdosing or chronic use could lead to neurotoxic effects similar to those observed with ketamine, affecting memory and cognitive function, especially in young adults.
Paper Details　
Original Abstract of the Article :
In several countries, including the Netherlands, the use of GHB seems to be rising. GHB is regarded by recreational users as an innocent drug without any side effects. Recently, the number of patients in treatment due to GHB addiction sharply increased. In addition, various studies report incidents ...See full text at original site
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引用元：
https://doi.org/10.1016/j.neubiorev.2012.02.002

データ提供：米国国立医学図書館（NLM）

GHB: A Closer Look at the Potential Long-Term Effects of This Popular Drug

This study examines the potential long-term effects of γ-hydroxybutyric acid (GHB), a drug known for its sedative and euphoric properties. While often perceived as harmless, GHB can have unintended consequences, particularly when used recreationally or in overdose. The researchers explore the potential neurotoxic effects of GHB, focusing on its impact on memory and cognitive function. Think of the brain as a delicate oasis in the desert of our bodies, susceptible to the harsh effects of toxins and overuse. The researchers delve into the potential neurotoxic effects of GHB, like a caravan of explorers navigating the desert, seeking to understand the impact of this drug on the delicate oasis of our minds.

GHB: A Hidden Oasis in the Desert of Neuroscience

The study raises important questions about the potential neurotoxic effects of GHB, urging researchers to further investigate its long-term impact on brain function. It's like exploring a hidden oasis in the vast desert of neuroscience, where researchers strive to uncover the secrets of brain health and the potential hazards of certain substances. The study highlights the need for greater awareness of the potential risks associated with GHB use, encouraging individuals to be mindful of the potential consequences of recreational drug use.

Protecting the Oasis: A Call for Caution and Research

The study serves as a reminder to be cautious when using any substances, particularly those with known potential for neurotoxicity. It's like protecting a precious oasis in the heart of the desert, a place where careful stewardship is essential for its survival. The researchers encourage further research into the long-term effects of GHB, emphasizing the importance of safeguarding our cognitive health and well-being.

Dr. Camel's Conclusion

This study urges us to be mindful of the potential long-term effects of GHB, even when used recreationally. It's like navigating a vast desert, where seemingly harmless shortcuts can lead to unintended consequences. The research encourages further investigation into the neurotoxic potential of GHB, emphasizing the importance of protecting the delicate oasis of our minds.
Date :
  1. Date Completed 2012-07-16
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

22342779

DOI: Digital Object Identifier

10.1016/j.neubiorev.2012.02.002

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English

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