Efficacy and tolerability of lasmiditan, an oral 5-HT(1F) receptor agonist, for the acute treatment of migraine: a phase 2 randomised, placebo-controlled, parallel-group, dose-ranging study.

Author: , DienerHans-Christoph, FärkkiläMarkus, GéraudGilles, HarnerNadja, LáinezMiguel, PilgrimAlison, ReuterUwe, SchoenenJean

Paper Details 
Original Abstract of the Article :
Lasmiditan (COL-144) is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist without vasoconstrictor activity that seemed effective when given as an intravenous infusion in a proof-of-concept migraine study. We aimed to assess the efficacy and safety of oral lasmiditan for the acute...See full text at original site
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引用元:
https://doi.org/10.1016/S1474-4422(12)70047-9

データ提供:米国国立医学図書館(NLM)

Lasmiditan: A Promising Treatment for Acute Migraine

This phase 2 clinical trial investigates the efficacy and safety of lasmiditan, a novel 5-HT(1F) receptor agonist, for the acute treatment of migraine. The study found that lasmiditan, administered orally, was effective in reducing migraine symptoms and was generally well-tolerated. The findings suggest that lasmiditan could be a valuable addition to the therapeutic options for acute migraine treatment.

A New Frontier in Migraine Treatment: The Promise of Lasmiditan

The results of this clinical trial demonstrate the potential of lasmiditan as an effective and well-tolerated treatment for acute migraine. The study's findings offer hope for those seeking relief from migraine attacks, potentially providing a new avenue for managing this debilitating condition. Further research and clinical trials are needed to confirm the long-term efficacy and safety of lasmiditan in a wider population.

Navigating the Desert of Migraine: Seeking Relief from the Storm

Migraine, like a desert sandstorm, can be a relentless and debilitating force. This study offers a glimmer of hope, demonstrating the potential of lasmiditan to provide relief from migraine attacks. It underscores the need for ongoing research and development of new and effective treatments to alleviate the suffering associated with this common and often challenging condition.

Dr. Camel's Conclusion

Migraine, like a relentless desert wind, can bring a sudden and intense storm of discomfort. This research offers hope for a new way to tame the storm, demonstrating the potential of lasmiditan to provide effective and safe relief from migraine attacks. While further research is needed, this study is a promising step forward in the search for better migraine treatments.
Date :
  1. Date Completed 2012-06-06
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

22459549

DOI: Digital Object Identifier

10.1016/S1474-4422(12)70047-9

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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