Blood pressure effects of high-dose amlodipine-benazepril combination in Black and White hypertensive patients not controlled on monotherapy.

Author: ChrysantSteven G

Paper Details 
Original Abstract of the Article :
BACKGROUND: Black hypertensive patients are more resistant to angiotensin-converting enzyme (ACE) inhibitor monotherapy than White patients. This resistance can be overcome with the combination of ACE inhibitors with diuretics or calcium-channel blockers (CCBs). OBJECTIVES: The objective of this cl...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586097/

データ提供:米国国立医学図書館(NLM)

Blood Pressure Effects of High-Dose Amlodipine-Benazepril in Black and White Hypertensive Patients

This study delves into the fascinating world of hypertension, exploring the effectiveness of a combination therapy involving amlodipine, a calcium-channel blocker, and benazepril, an angiotensin-converting enzyme (ACE) inhibitor, in Black and White hypertensive patients. The researchers, like skilled pharmacists compounding a potent remedy, are seeking a more effective treatment for hypertension, a condition that disproportionately affects Black individuals.

The study found that the combination therapy resulted in greater blood pressure lowering than either drug alone, particularly in Black patients who often exhibit resistance to ACE inhibitors. This is like a desert traveler finding a more efficient way to reach an oasis, overcoming obstacles and finding a more effective path.

Effective Treatment for Hypertension

This research offers promising results for the treatment of hypertension, particularly in Black patients. The study's findings, like the discovery of a wellspring in a parched desert, offer hope for individuals struggling with this condition.

Health Implications and Everyday Applications

This research emphasizes the importance of tailoring treatment strategies to individual patient needs. It's like understanding the diverse plant life in a desert, each species having unique requirements for survival. Individuals with hypertension should consult with their healthcare providers to discuss the most appropriate treatment options for their specific needs and risk factors.

Dr.Camel's Conclusion

This study showcases the importance of personalized medicine, highlighting that a one-size-fits-all approach to hypertension is often insufficient. It's like navigating a desert with a diverse landscape, requiring different strategies for different terrains. This research encourages a more personalized approach to treatment and opens the door to further research exploring the effectiveness of combination therapies in managing hypertension.

Date :
  1. Date Completed 2012-10-29
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

22571394

DOI: Digital Object Identifier

PMC3586097

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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