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Differential effects of busulfan on gonadal development in five divergent anuran species.

Author: KubiakJacek Z, PecioAnna, PiprekRafał P, SzymuraJacek M

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the role of germ cells, the precursor cells of sperm and eggs, in the development of gonads in five frog species. The study found that germ cells are not required for the initial formation of the gonads but are necessary for their differentiation into ovaries and for maintaining the structure of the gonads.
Paper Details　
Original Abstract of the Article :
The aim of this paper was to investigate the effects of germ cell depletion on the sexual differentiation of gonads in five anuran species. We used busulfan to eliminate the germ cells. Our results indicate that germ cells are not required for gonadal ridge formation or the development of the undiff...See full text at original site
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引用元：
https://doi.org/10.1016/j.reprotox.2012.05.002

データ提供：米国国立医学図書館（NLM）
in preparation
Date :
  1. Date Completed 2013-01-24
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

22609225

DOI: Digital Object Identifier

10.1016/j.reprotox.2012.05.002

Related Literature

Article Analysis
・Effects of busulfan
SNS
PICO Info
in preparation
Languages

English

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