Paper Details

  1. Home
  2. Paper Details

"Spice" and "K2" herbal highs: a case series and systematic review of the clinical effects and biopsychosocial implications of synthetic cannabinoid use in humans.

Author: Ait-DaoudNassima, GundersonErik W, HartCarl L, HaugheyHeather M, JoshiAmruta S

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This systematic review examines the clinical effects of synthetic cannabinoids (SCs) in humans, highlighting potential toxicity such as anxiety and psychosis. The review also presents three case reports of individuals who used SCs to alleviate cannabis withdrawal.
Paper Details　
Original Abstract of the Article :
Cannabis, the most commonly used illicit substance, exerts its primary psychoactive effect via delta-9 tetrahydrocannabinol (Δ(9) -THC) agonism of cannabinoid receptor type 1 (CB1). Some users develop a cannabis use disorder and physical dependence manifested by withdrawal symptoms during abstinence...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1111/j.1521-0391.2012.00240.x

データ提供：米国国立医学図書館（NLM）

Spice and K2: Exploring the Uncharted Territories of Synthetic Cannabinoids

The world of [psychoactive substances] is constantly evolving, with new and often unpredictable substances emerging. This study focuses on the effects of synthetic cannabinoids, commonly marketed as 'Spice' and 'K2,' which are gaining popularity as alternatives to traditional cannabis. The researchers conducted a systematic review of published reports and documented three cases involving experienced marijuana users who regularly consumed these synthetic products.

Unmasking the Mystery: Exploring the Effects of Synthetic Cannabinoids

The study revealed a complex picture, with some reports highlighting potential toxicity, such as acute anxiety and psychosis. However, the three documented cases showed overlapping effects with marijuana, with individuals reporting that the synthetic products effectively alleviated cannabis withdrawal symptoms. This suggests a complex interplay between synthetic cannabinoids and the body, much like the intricate ecosystem of a desert, where different elements interact in unexpected ways.

Navigating the Unknown: Understanding the Risks and Benefits

The growing popularity of 'Spice' and 'K2' raises concerns about their potential for abuse and dependence. The study highlights the need for further research to fully understand the long-term effects of these synthetic cannabinoids, ensuring the safety and well-being of users. It's like venturing into a new desert region, where caution and exploration are essential to unravel its mysteries and potential dangers.

Dr.Camel's Conclusion

This research provides valuable insights into the emerging world of synthetic cannabinoids, highlighting the potential for both benefits and risks. It's like encountering a mirage in the desert, where the allure of a refreshing oasis might be deceptive. Further research is crucial to navigate the complex landscape of these synthetic substances and ensure the health and safety of those who use them.

Date :
  1. Date Completed 2012-09-14
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

22691010

DOI: Digital Object Identifier

10.1111/j.1521-0391.2012.00240.x

Related Literature

Article Analysis
・Effective treatment of marijuana
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.