Postmarketing surveillance of intussusception following mass introduction of the attenuated human rotavirus vaccine in Mexico.

Author: BlumMaxim, BreuerThomas, Cervantes-ApolinarMariaYolanda, ColindresRomulo E, DeAntonio-SuarezRodrigo, GrajalesConcepción, HernándezM Teresa, MercadilloMaría Guadalupe, Ortega-BarriaEduardo, TorresF Javier, VelázquezF Raúl, VerstraetenThomas

Paper Details 
Original Abstract of the Article :
BACKGROUND: Mexico initiated mass vaccination with the attenuated human rotavirus vaccine (Rotarix) in 2006. This postlicensure study aimed to assess any potential temporal association between vaccination and intussusception in Mexican infants. METHODS: Prospective, active surveillance for intussus...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/22695189

データ提供:米国国立医学図書館(NLM)

Rotavirus Vaccine: A Lifeline in the Desert of Childhood Disease

Rotavirus is a common cause of severe diarrhea in children, leading to significant morbidity and mortality globally. This study investigates the potential association between the introduction of the rotavirus vaccine and the incidence of intussusception, a serious condition affecting the intestines.

Navigating the Complexities of Vaccination: Rotavirus Vaccine and Intussusception

The researchers conducted a large-scale surveillance study, analyzing the relationship between rotavirus vaccination and intussusception in Mexican infants. They found a temporal association between the first dose of the vaccine and an increased risk of intussusception, but the overall impact of vaccination on the incidence of intussusception remains unclear. This highlights the complex nature of vaccine safety and the need for ongoing monitoring and research.

Balancing Benefits and Risks: Rotavirus Vaccination and Intussusception

This research provides crucial insights into the potential risks and benefits of rotavirus vaccination. It's like trying to find a balance between the harsh realities of a desert and the promise of a hidden oasis – the benefits of vaccination outweigh the risks, but it's important to remain aware of the potential complications.

Dr.Camel's Conclusion

This study underscores the importance of ongoing research and surveillance to ensure the safety and efficacy of vaccines, even those with significant benefits. It's like exploring a new desert – we need to be prepared for unexpected terrain and adjust our path accordingly. Vaccination remains a vital tool in protecting children, but understanding its complexities is essential for ensuring its continued success.

Date :
  1. Date Completed 2012-10-02
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

22695189

DOI: Digital Object Identifier

00006454-201207000-00016

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.