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Simplification to dual antiretroviral therapy including a ritonavir-boosted protease inhibitor in treatment-experienced HIV-1-infected patients.
Author: BurgosJoaquin, CrespoManuel, CurranAdria, DomingoPere, FalcóVicenç, ImazArkaitz, MateoM Gracia, NavarroJordi, PahissaAlbert, PodzamczerDaniel, RiberaEsteve, Van den EyndeEva, VillarSara
Original Abstract of the Article :
OBJECTIVES: To assess the effectiveness of simplification to a dual antiretroviral regimen containing a ritonavir-boosted protease inhibitor (PI/r) in treatment-experienced HIV-1-infected patients. METHODS: Retrospective analysis of 131 HIV-1-infected patients on suppressive antiretroviral treatmen...See full text at original site
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引用元：
https://doi.org/10.1093/jac/dks227
データ提供：米国国立医学図書館（NLM）
Simplifying Antiretroviral Therapy: A Journey Toward Improved Adherence
This study explores the effectiveness of [simplifying antiretroviral therapy] for [HIV-1-infected patients] who are already on [suppressive antiretroviral treatment]. The researchers conducted a [retrospective analysis] of [131 patients] who switched to a [maintenance dual antiretroviral regimen] containing a [ritonavir-boosted protease inhibitor (PI/r)]. The study aimed to assess the effectiveness and safety of this simplified treatment approach.
A Streamlined Path: Reducing the Burden of Antiretroviral Therapy
The study found that [simplification to a dual-therapy regimen including a PI/r might be useful to enhance convenience and/or diminish toxicity in selected treatment-experienced patients]. The researchers observed that [90.1% of patients] remained [free of therapeutic failure] at the end of follow-up, with [median follow-up of 14 months]. The study suggests that [simplifying to a dual therapy regimen containing a PI/r] may be a viable option for improving adherence to treatment and potentially enhancing patient quality of life.
A Brighter Future: Navigating the Complexities of HIV Treatment
This research highlights the ongoing efforts to improve the management of HIV infection. The study's findings suggest that [simplifying treatment regimens] can potentially improve adherence and reduce the burden of therapy. This research underscores the importance of [personalized treatment strategies], tailoring therapy to individual patient needs and goals.
Dr. Camel's Conclusion
The journey of living with HIV is a challenging one, navigating a complex desert of treatment options. This study explores a simplified path, potentially easing the burden of therapy for patients already on suppressive regimens. The findings offer a glimmer of hope for a brighter future, where HIV treatment is more manageable and patient-centered.
Date :
- Date Completed 2013-01-09
- Date Revised 2013-11-21
Further Info :
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