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Modafinil as a replacement for dextroamphetamine for sustaining alertness in military helicopter pilots.

Author: AthyJeremy R, CrowleyJohn S, EstradaArthur, KelleyAmanda M, WebbCatherine M

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.

Overview

Modafinil, a stimulant with a low affinity for dopamine uptake binding sites, has been evaluated for its efficacy and safety during actual helicopter flight operations. The study found that modafinil was effective and safe, providing support for its potential use as an alternative to dextroamphetamine in military aviation.
Paper Details　
Original Abstract of the Article :
Successful military aviation operations depend on maintaining continuous day-night operations. Stimulants are easy to use and popular for sustaining performance because their utility is not dependent upon environmental or scheduling modifications. Dextroamphetamine is authorized for use by the aircr...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.3357/asem.3129.2012

データ提供：米国国立医学図書館（NLM）

Modafinil: A Safer Alternative for Sustaining Alertness in Military Pilots?

Military aviation operations often demand sustained alertness, even during long and challenging flights. This study investigates the potential of modafinil, a wakefulness-promoting drug, as a safer alternative to dextroamphetamine for sustaining alertness in helicopter pilots. Researchers aimed to establish the efficacy and safety of modafinil during actual flying operations. Their findings suggest that modafinil is effective in maintaining alertness and performance during flight operations. The researchers also found that modafinil displays a lower affinity for dopamine uptake binding sites, reducing the risk of abuse and addiction. This research offers a promising path towards safer and more effective methods for sustaining alertness in high-demand professions.

Modafinil: A Potential Game-Changer for Military Aviation?

This study presents a compelling case for modafinil as a safer and potentially more effective alternative to dextroamphetamine for sustaining alertness in military pilots. By demonstrating efficacy during actual flying operations and showcasing its lower risk for abuse and addiction, this research could pave the way for a paradigm shift in the management of pilot alertness. It's like finding a more reliable and less treacherous path through the desert of flight operations.

Safety First: Navigating the Landscape of Alertness

Maintaining alertness in demanding professions like military aviation is paramount. This research highlights the importance of exploring and implementing safer and more effective methods for achieving and sustaining alertness, ensuring the safety and well-being of individuals performing these crucial tasks.

Dr.Camel's Conclusion

This research offers a promising glimpse into the potential of modafinil as a safer and more effective alternative to dextroamphetamine for sustaining alertness in military pilots. By reducing the risk of abuse and addiction, modafinil could provide a more sustainable and reliable solution for maintaining performance during demanding flight operations. It's like finding a hidden oasis of safety and effectiveness in the vast desert of military aviation.

Date :
  1. Date Completed 2012-08-02
  2. Date Revised 2019-10-27
Further Info :

Pubmed ID

22764609

DOI: Digital Object Identifier

10.3357/asem.3129.2012

Related Literature

Article Analysis
・Side Effects of dextroamphetamine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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