Risk of insomnia attributable to β-blockers in elderly patients with newly diagnosed hypertension.

Author: ChangChia-Hsien, ChengChing-Lan, LinLi-Jen, LinSwu-Jane, SuJyun-Jhong, YangYea-Huei Kao

Paper Details 
Original Abstract of the Article :
Use of β-blockers may cause insomnia and central nervous system and/or psychological side effects, but data are limited on the relative risks of insomnia among β-blockers. This retrospective cohort study used Taiwan's National Health Insurance claims database from 2003 to 2007, where 4,063 patients ...See full text at original site
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引用元:
https://doi.org/10.2133/dmpk.dmpk-12-rg-004

データ提供:米国国立医学図書館(NLM)

β-Blockers and Insomnia in Elderly Hypertension Patients

Hypertension, or high blood pressure, is a common condition that affects millions worldwide. It's like a persistent desert wind, putting stress on the cardiovascular system. While β-blockers are often used to manage hypertension, they can sometimes cause insomnia, a condition that disrupts sleep and makes it difficult to function during the day. This study investigated the risk of insomnia associated with various β-blockers in elderly patients with newly diagnosed hypertension. The researchers aimed to identify specific β-blockers that might be associated with a lower risk of insomnia, a quest like seeking a cool oasis in a scorching desert.

Bisoprolol and Atenolol: Potential Solutions for Insomnia

The study found that the risk of insomnia was significantly lower for patients taking bisoprolol and atenolol compared to those taking propranolol, a commonly used β-blocker. This is like finding a hidden spring of fresh water in the desert - a welcome relief! The study suggests that these specific β-blockers might be a better choice for elderly hypertension patients who are susceptible to insomnia.

Choosing the Right β-Blocker for Optimal Sleep

The study also highlighted the importance of considering the selectivity and lipophilicity of β-blockers when choosing a medication for elderly patients. β-blockers with high selectivity for β1-receptors and low lipophilicity were associated with a lower risk of insomnia. This is like selecting the right type of camel for a journey across the desert - some camels are better suited for certain terrains and conditions. The study provides valuable insights for physicians seeking to optimize treatment for elderly hypertension patients while minimizing the risk of insomnia.

Dr.Camel's Conclusion

Navigating the world of β-blockers and insomnia can be tricky, like finding your way through a vast, starless night. This study offers a guiding star, suggesting that specific β-blockers like bisoprolol and atenolol might offer a better sleep experience for elderly patients with hypertension.

Date :
  1. Date Completed 2013-08-14
  2. Date Revised 2019-11-12
Further Info :

Pubmed ID

22813717

DOI: Digital Object Identifier

10.2133/dmpk.dmpk-12-rg-004

Related Literature

SNS
PICO Info
in preparation
Languages

English

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