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Safety evaluation of lubiprostone in the treatment of constipation and irritable bowel syndrome.

Author: ChamberlainSherman M, RaoSatish S C

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Lubiprostone, a medication for constipation, causes fluid and electrolyte secretion in the small bowel, leading to laxation. While generally safe and effective, common side effects include nausea, diarrhea, abdominal pain, and bloating.
Paper Details　
Original Abstract of the Article :
Lubiprostone is approved in the United States for the treatment of chronic idiopathic constipation and constipation predominant irritable bowel syndrome (IBS-C). Lubiprostone causes secretion of fluid and electrolytes in the small bowel, through the activation of chloride channels, and thereby induc...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1517/14740338.2012.708732

データ提供：米国国立医学図書館（NLM）

Lubiprostone: A Gentle Breeze in the Desert of Constipation

Constipation, a common and often uncomfortable condition, can be a frustrating journey. This research examines lubiprostone, a medication approved to treat chronic constipation and irritable bowel syndrome with constipation (IBS-C). Like a gentle desert breeze that helps clear the air, lubiprostone works by stimulating fluid secretion in the small intestine, promoting bowel movement. Researchers explored the safety and effectiveness of lubiprostone, finding it to be generally well-tolerated, with common side effects like nausea, diarrhea, and abdominal pain.

Finding Relief in the Desert of Digestive Discomfort

The study's findings suggest that lubiprostone can effectively alleviate constipation and IBS-C, offering relief for many individuals struggling with these conditions. It's like discovering a hidden oasis in the desert, providing a much-needed respite from the discomfort of constipation. The research highlights the importance of exploring effective treatments for these conditions, providing hope for improved digestive health and quality of life.

The Desert of Digestive Health

Navigating the desert of digestive health can be a challenging journey. This research provides a glimmer of hope for those struggling with constipation and IBS-C, offering a potential path to relief and improved comfort.

Dr.Camel's Conclusion

The research on lubiprostone highlights the importance of finding effective treatments for constipation and IBS-C, offering a potential path to improved digestive health and quality of life. It's like finding a refreshing oasis in the midst of a challenging desert journey.

Date :
  1. Date Completed 2013-01-21
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

22834474

DOI: Digital Object Identifier

10.1517/14740338.2012.708732

Related Literature

Article Analysis
・Side Effects of lubiprostone
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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