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Cardiovascular side effects of aminophylline in meconium-induced acute lung injury.

Author: CalkovskaA, HutkoM, MokraD, MokryJ, PetraskovaM, TonhajzerovaI

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Intravenous aminophylline, a PDE inhibitor, can cause acute cardiovascular changes in neonatal meconium aspiration syndrome, leading to increased blood pressure and heart rate.
Paper Details　
Original Abstract of the Article :
As inflammation plays an important role in the pathogenesis of neonatal meconium aspiration syndrome (MAS), anti-inflammatory agents including inhibitors of phosphodiesterases (PDE) are increasingly used in the treatment. To evaluate side effects of PDE inhibitors, this study analyzed changes in blo...See full text at original site
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引用元：
https://doi.org/10.1007/978-94-007-4549-0_41

データ提供：米国国立医学図書館（NLM）

Cardiovascular Side Effects of Aminophylline in Meconium-Induced Acute Lung Injury

The delicate balance of the cardiovascular system is vital for life. This study investigates the potential cardiovascular side effects of aminophylline, a drug used in the treatment of meconium-induced acute lung injury (MAS). The study analyzed changes in blood pressure, heart rate, and heart rate variability in rabbits with MAS, providing valuable insights into the potential cardiovascular risks associated with aminophylline use.

Aminophylline and Cardiovascular Side Effects

The study found that aminophylline administration led to acute cardiovascular changes in rabbits with MAS. This underscores the importance of careful monitoring and consideration of potential cardiovascular risks when using aminophylline for treating MAS. The findings highlight the delicate balance that must be maintained when navigating the complex interplay between respiratory and cardiovascular systems.

Careful Monitoring of Cardiovascular Health

This research emphasizes the importance of careful monitoring of cardiovascular health when using aminophylline for treating MAS. It's like navigating a desert – you need to be aware of potential hazards and take precautions to ensure a safe journey.

Dr. Camel's Conclusion

This study highlights the potential cardiovascular side effects of aminophylline in the treatment of MAS. Careful monitoring and consideration of cardiovascular risks are essential when using this medication. It's like traversing a desert – you need to be aware of potential hazards and take precautions to ensure a safe journey.

Date :
  1. Date Completed 2012-12-03
  2. Date Revised 2016-11-09
Further Info :

Pubmed ID

22836652

DOI: Digital Object Identifier

10.1007/978-94-007-4549-0_41

Related Literature

Article Analysis
・Side Effects of aminophylline
SNS
PICO Info
in preparation
Languages

English

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