[Clinical evaluation of a new oral cephem, cefdinir, in children].

Author: AbeT, MeguroH, TajimaT

Paper Details 
Original Abstract of the Article :
Cefdinir (CFDN, FK482) was evaluated for its safety, efficacy and pharmacokinetics in 28 children. CFDN was effective in 100% of 22 evaluable cases with respiratory, middle ear, urinary or soft tissue infections. From the clinical response, adverse effects and the pharmacokinetic results, daily dose...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/2283714

データ提供:米国国立医学図書館(NLM)

Cefdinir: A New Cephem for Pediatric Infections

This study investigates the effectiveness of cefdinir (CFDN), a new oral cephem antibiotic, in treating infections in children. CFDN was tested for its safety, efficacy, and pharmacokinetic properties in a group of 28 children. The researchers found that CFDN effectively treated respiratory, middle ear, urinary, and soft tissue infections in all 22 evaluable cases. Based on the clinical response, adverse effects, and pharmacokinetic data, the researchers recommend a daily dose of 9-18 mg/kg, administered in three divided portions. They also observed that increasing the dose may lead to increased gastrointestinal side effects.

CFDN Shows Promise for Pediatric Infections

The study demonstrated that CFDN is a safe and effective treatment option for children suffering from infections caused by susceptible bacteria, including Staphylococcus aureus. The findings suggest that CFDN can be a valuable addition to the treatment arsenal for pediatric infections.

Cefdinir: A Boon for Pediatric Care

The successful use of CFDN in treating various infections in children provides a welcome addition to the treatment options for young patients. This research highlights the importance of developing targeted treatments for specific age groups and demonstrates the potential of CFDN to improve the health and well-being of children.

Dr.Camel's Conclusion

Just as a camel adapts to the harsh conditions of the desert, cefdinir proves to be a versatile and effective treatment for infections in children. The study's findings offer valuable insights into the treatment of pediatric infections, providing healthcare providers with a new tool to combat these conditions.

Date :
  1. Date Completed 1991-03-18
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

2283714

DOI: Digital Object Identifier

2283714

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Languages

Japanese

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