MRI inflammation and its relation with measures of clinical disease activity and different treatment responses in patients with ankylosing spondylitis treated with a tumour necrosis factor inhibitor.

Author: BakerDaniel, BaraliakosXenofon, BraunJürgen, HermannKay-Geert A, HsuBenjamin, LandewéRobert B M, MachadoPedro, van der HeijdeDésirée

Paper Details 
Original Abstract of the Article :
OBJECTIVES: To investigate the relationship between MRI inflammation and measures of clinical disease activity as well as treatment responses in patients with ankylosing spondylitis (AS) treated with a tumour necrosis factor inhibitor. METHODS: MRI at baseline (n=221), 24 (n=158) and 102 weeks (n=1...See full text at original site
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引用元:
https://doi.org/10.1136/annrheumdis-2012-201999

データ提供:米国国立医学図書館(NLM)

MRI Inflammation and Treatment Response in Ankylosing Spondylitis

This study delves into the relationship between MRI inflammation and clinical disease activity in patients with ankylosing spondylitis (AS) undergoing treatment with a tumor necrosis factor inhibitor. It’s like carefully examining the tracks of a caravan in the desert, revealing the journey and impact of the travelers. The study found that MRI inflammation scores correlated better with C-reactive protein (CRP) levels than with other measures of disease activity. This information can help clinicians better assess disease activity and tailor treatment plans.

MRI as a Biomarker for Ankylosing Spondylitis

The study demonstrated a strong correlation between MRI inflammation scores and CRP levels, suggesting that MRI may be a valuable tool for monitoring disease activity in AS patients. It’s like using a compass to navigate a vast desert, ensuring the traveler stays on course. The research also highlighted the importance of combining objective and subjective measures, like CRP and patient-reported outcomes, for a more comprehensive assessment of disease activity.

Improving Treatment Outcomes in Ankylosing Spondylitis

This research offers valuable insights into the management of ankylosing spondylitis. It’s like discovering a new oasis in the desert, providing a refuge for those seeking relief. The study suggests that MRI can be a useful tool for monitoring disease activity in AS patients, particularly in conjunction with CRP levels. This information could help clinicians optimize treatment plans and improve patient outcomes.

Dr.Camel's Conclusion

This research explores the role of MRI in assessing and monitoring disease activity in ankylosing spondylitis (AS). It’s like a careful observation of the changing landscape of a desert, revealing the dynamic nature of this complex disease. The study suggests that MRI can be a valuable tool for guiding treatment decisions and improving patient outcomes, offering a ray of hope for individuals living with AS.

Date :
  1. Date Completed 2013-01-14
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

22915615

DOI: Digital Object Identifier

10.1136/annrheumdis-2012-201999

SNS
PICO Info
in preparation
Languages

English

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