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Development, in vitro and in vivo evaluation of novel injectable smart gels of azithromycin for chronic periodontitis.
Author: AvinashB S, KumarG Sheela, KumarT M Pramod, VenkateshM P
Original Abstract of the Article :
Periodontitis is an inflammatory condition affecting teeth resulting in progressive destruction of periodontal ligaments, resorption of alveolar bone and loss of teeth. Treatment of periodontitis includes surgical and non surgical management. Systemic antibiotics are also used for the treatment of p...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.2174/1567201811310020005
データ提供:米国国立医学図書館(NLM)
Injectable Smart Gels of Azithromycin for Chronic Periodontitis
Chronic periodontitis is a challenging oral health condition, like a persistent desert storm that can erode the foundations of our teeth. This study explores a novel approach to treating chronic periodontitis using injectable smart gels of azithromycin, a commonly used antibiotic. Think of this as a targeted solution, like a camel caravan carefully navigating a treacherous path to reach a distant oasis.Smart Gels for Targeted Drug Delivery
The study focused on developing biodegradable, thermosensitive gels of azithromycin. This innovative approach aimed to provide controlled release of the drug at the site of infection, ensuring localized therapy and minimizing systemic exposure. Imagine these gels as a protective layer, like a camel's thick coat shielding it from the harsh desert sun. The study found that the smart gels were well-tolerated and demonstrated significant improvement in clinical parameters, such as gingival index and probing pocket depth.The Future of Chronic Periodontitis Treatment
This research holds promise for the future of chronic periodontitis treatment. By developing smart gels that can deliver antibiotics directly to the affected area, we can potentially improve patient outcomes and minimize the need for more invasive procedures. Think of these gels as a beacon of hope, illuminating a path toward improved oral health for patients with chronic periodontitis.Dr.Camel's Conclusion
The desert of oral health is a complex and challenging landscape, but with innovative technologies and research, we can find new solutions. This study provides exciting evidence for the potential of smart gels in treating chronic periodontitis, offering a more targeted and efficient approach. By continuing to explore the vast desert of oral health, we can discover new therapies that improve the lives of millions.Date :
- Date Completed 2013-09-26
- Date Revised 2019-11-12
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