Species differences in the antidiarrheal and antispasmodic activities of Lepidium sativum and insight into underlying mechanisms.

Author: AlkharfyKhalid M, GilaniAnwarul-Hassan, MehmoodMalik Hassan, RehmanNajeeb-Ur

Paper Details 
Original Abstract of the Article :
The aim of this study was to see if the crude extract of Lepidium sativum (Ls.Cr) exhibits species specificity in its antidiarrheal and antispasmodic activities along with insight into the underlying mechanisms using the in-vivo and in-vitro experiments. Ls.Cr inhibited castor oil-induced diarrhea i...See full text at original site
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引用元:
https://doi.org/10.1002/ptr.4819

データ提供:米国国立医学図書館(NLM)

Species Specificity in Antidiarrheal and Antispasmodic Activities of Lepidium sativum

In the vast desert of [pharmacology], the quest for effective treatments is a constant journey. This study delves into the potential of [Lepidium sativum] as a source of [antidiarrheal and antispasmodic agents]. The researchers investigated the [species specificity] of [Lepidium sativum] in its [antidiarrheal and antispasmodic activities], using both [in vivo] and [in vitro] experiments. They aimed to uncover the underlying mechanisms by which [Lepidium sativum] exerts its effects.

Unraveling the Mystery of Lepidium sativum

This research reveals a fascinating aspect of [Lepidium sativum]'s effects – its [species specificity]. The authors found that [Lepidium sativum] exhibits varying levels of [antidiarrheal and antispasmodic activity] across different animal species. This underscores the importance of considering [species specificity] when evaluating the potential of [medicinal plants] for treating [human conditions]. The study also provides insights into the complex mechanisms underlying these activities, suggesting that [Lepidium sativum] exerts its effects through multiple pathways, including [activation of K+ channels, inhibition of muscarinic receptors, Ca++ channels, and PDE enzyme].

Exploring the Diverse World of Medicinal Plants

This study serves as a reminder of the [diverse nature] of [medicinal plants] and their effects on different organisms. It emphasizes the importance of comprehensive research to fully understand the [pharmacological profile] of any potential [medicinal product]. This knowledge is crucial in developing [safe and effective treatments] for various [human conditions].

Dr.Camel's Conclusion

Just as the desert is home to a diverse array of plants, each with unique properties, so too is the world of medicinal plants. This research reminds us that we must explore these diverse resources with care and thoroughness, ensuring that we fully understand their potential benefits and risks before utilizing them for human health.

Date :
  1. Date Completed 2014-06-05
  2. Date Revised 2019-03-18
Further Info :

Pubmed ID

23007892

DOI: Digital Object Identifier

10.1002/ptr.4819

Related Literature

SNS
PICO Info
in preparation
Languages

English

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