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Tibenelast, 5,6-diethoxybenzo(B)thiophene-2-carboxylic acid, sodium salt (LY186655), is an orally active anti-asthma compound in the guinea pig.
Author: BertschB, EstermanM, HoP P, PanettaJ A
Original Abstract of the Article :
Anaphylactic shock was induced in actively sensitized guinea pigs by free inhalation of a high dose of ovalbumin (10 mg/ml) aerosol. Tibenelast (LY186655), 5,6-diethoxybenzo(b)-thiophene-2-carboxylic acid, sodium salt, proved to be a potent orally active compound against anaphylactic shock induced b...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/0024-3205(90)90093-7
データ提供:米国国立医学図書館(NLM)
Tibenelast: A Promising New Anti-Asthma Compound
Asthma is a chronic respiratory disease that affects millions of people worldwide. This study explores the potential of tibenelast (LY186655), a novel compound, as a treatment for asthma. The researchers found that tibenelast was effective in preventing anaphylactic shock and bronchoconstriction in guinea pigs, demonstrating its potential as an orally active anti-asthma drug. The authors suggest that tibenelast may work at a different site than epinephrine, offering a potential for synergy with existing treatments.
A New Path Through the Desert of Asthma: Tibenelast as a Potential Solution
This study offers a glimmer of hope for those struggling with asthma. It's like discovering a new pathway through a vast and challenging desert. This research suggests that tibenelast could offer a valuable new treatment option for asthma, potentially providing relief for millions of patients.
Navigating the Desert of Asthma: Finding the Right Treatment
This study emphasizes the importance of finding the most effective treatment for each individual with asthma. It's like navigating a desert, where different paths lead to different destinations. This research suggests that tibenelast could offer a new and potentially more effective route for some patients, providing a new source of hope for managing this chronic condition.
Dr. Camel's Conclusion
This study provides a compelling case for the potential of tibenelast as a new anti-asthma drug. It's like finding a hidden oasis in the desert, offering a refreshing new solution for managing this challenging condition. This research inspires us to continue exploring new treatment options for asthma, bringing us closer to a future where this debilitating disease is effectively managed.
Date :
- Date Completed 1990-05-30
- Date Revised 2019-07-01
Further Info :
Related Literature
English
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