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Lanthanum carbonate for the treatment of hyperphosphatemia in CKD 5D: multicenter, double blind, randomized, controlled trial in mainland China.

Author: ChenJiang-Hua, ChenXiang-Mei, DingGuo-Hua, FanYa-Ping, LiuZhi-Hong, MeiChang-Lin, NiZhao-Hui, WangLi-Ning, WangMei, XuJing, YuXue-Qing, YuanFa-Huan, ZhangAi-Ping, ZhangYi-Xiang

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Lanthanum carbonate is an efficacious and well-tolerated oral phosphate binder with a mild AE profile in hemodialysis and CAPD patients. This agent may provide an alternative for the treatment of hyperphosphatemia in CKD 5D patients in mainland China.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Serum phosphorus control is critical for chronic kidney disease (CKD) 5D patients. Currently, clinical profile for an oral phosphorus binder in the mainland Chinese population is not available. OBJECTIVE: To establish the efficacy, safety, and tolerability of lanthanum carbonate in CKD ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570485/

データ提供：米国国立医学図書館（NLM）

Lanthanum Carbonate: A Promising Treatment for Hyperphosphatemia in CKD 5D

This study evaluates the efficacy and safety of lanthanum carbonate, a medication used to bind phosphate in the gut and reduce hyperphosphatemia, a common complication of chronic kidney disease (CKD) stage 5D. The researchers conducted a multicenter, double-blind, randomized, controlled trial in mainland China, comparing lanthanum carbonate to placebo in patients with CKD 5D on hemodialysis or peritoneal dialysis. The study found that lanthanum carbonate was effective in reducing serum phosphorus levels and was well tolerated, with minimal side effects.

Lanthanum Carbonate: A Safe and Effective Treatment for Hyperphosphatemia

This study confirms the effectiveness and safety of lanthanum carbonate in treating hyperphosphatemia, a significant challenge in CKD 5D patients. The study found that lanthanum carbonate effectively reduced serum phosphorus levels and was well tolerated, suggesting that it could be a valuable therapeutic option for this patient population.

Improving Outcomes for CKD 5D Patients

This study underscores the importance of effective management of hyperphosphatemia in CKD 5D patients. The study suggests that lanthanum carbonate could be a valuable tool for controlling serum phosphorus levels and improving outcomes for this patient population.

Dr. Camel's Conclusion

This study provides valuable evidence for the efficacy and safety of lanthanum carbonate in treating hyperphosphatemia in CKD 5D patients. The findings suggest that lanthanum carbonate could be a valuable therapeutic option for improving outcomes in this patient population. Further research is needed to optimize treatment protocols and address the long-term effects of lanthanum carbonate therapy.
Date :
  1. Date Completed 2013-07-11
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

23379590

DOI: Digital Object Identifier

PMC3570485

Related Literature

Article Analysis
・Side Effects of lanthanum
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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