Comparison of clinical effects of psoriasis treatment regimens among calcipotriol alone, narrowband ultraviolet B phototherapy alone, combination of calcipotriol and narrowband ultraviolet B phototherapy once a week, and combination of calcipotriol and narrowband ultraviolet B phototherapy more than twice a week.

Author: IizukaHajime, Ishida-YamamotoAkemi, TakahashiHidetoshi, TsujiHitomi

Paper Details 
Original Abstract of the Article :
We compared the clinical efficacy of various psoriasis treatments among: (i) topical application of calcipotriol ointment twice daily (group I); (ii) topical application of calcipotriol ointment twice daily and narrowband ultraviolet B NB-UVB phototherapy once a week (group II); (iii) topical applic...See full text at original site
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引用元:
https://doi.org/10.1111/1346-8138.12102

データ提供:米国国立医学図書館(NLM)

The Quest for Effective Psoriasis Treatment

Psoriasis, a chronic inflammatory skin condition, can be a source of discomfort and distress. While various treatment options exist, finding the most effective and efficient regimen for each patient remains a challenge. This research compares the clinical efficacy of different treatment regimens for psoriasis, including topical calcipotriol alone, narrowband ultraviolet B (NB-UVB) phototherapy alone, and combinations of the two.

Comparing Treatment Regimens

The researchers randomly assigned 40 patients with psoriasis to four groups, each receiving a different treatment regimen for 12 weeks. They meticulously measured the severity of psoriasis using the Psoriasis Area and Severity Index (PASI) and assessed pruritus using a visual analog scale. The findings revealed that all treatment regimens, including topical calcipotriol alone, NB-UVB phototherapy alone, and combinations of the two, effectively reduced psoriasis severity and pruritus. However, the group receiving the combination of calcipotriol and NB-UVB phototherapy more than twice a week exhibited the most significant and rapid improvement in psoriasis symptoms.

Exploring the Desert of Psoriasis Treatment

This research sheds light on the effectiveness of different treatment regimens for psoriasis, providing valuable insights for clinicians seeking to optimize treatment plans. It's like navigating a vast and arid desert, searching for the most effective path to healing.

Health Implications and Applications

This research offers valuable guidance for clinicians treating patients with psoriasis, suggesting that combining topical calcipotriol with NB-UVB phototherapy more than twice a week may be a more effective approach. It's like finding a hidden oasis in the desert of psoriasis treatment, offering a more efficient and rapid path to relief.

Dr. Camel's Conclusion

This research provides a comparative analysis of various treatment regimens for psoriasis, suggesting that combining topical calcipotriol with NB-UVB phototherapy more than twice a week may offer the most effective approach to reducing psoriasis severity and pruritus. It's like finding a hidden oasis in the desert of psoriasis treatment, offering a potential path to quicker and more effective relief.
Date :
  1. Date Completed 2014-07-14
  2. Date Revised 2014-11-20
Further Info :

Pubmed ID

23414298

DOI: Digital Object Identifier

10.1111/1346-8138.12102

Related Literature

SNS
PICO Info
in preparation
Languages

English

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