Clinical effects of gemifloxacin on the delay of tuberculosis treatment.

Author: ChungHee Soon, HeoEun Young, KimDeog Kyeom, KimSeo Yun, LeeChang-Hoon, ParkJong Sun, ParkSung Soo, YimJae-Joon

Paper Details 
Original Abstract of the Article :
Although gemifloxacin has low in vitro activity against Mycobacterium tuberculosis, the effect of gemifloxacin on the delay of tuberculosis (TB) treatment has not been validated in a clinical setting. The study group included patients with culture-confirmed pulmonary TB who initially received gemifl...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594600/

データ提供:米国国立医学図書館(NLM)

Gemifloxacin and Tuberculosis: A Case of Delayed Diagnosis?

The field of [infectious diseases] is constantly battling against the emergence of antibiotic-resistant bacteria. This research delves into the potential impact of [gemifloxacin] on the timely diagnosis of [tuberculosis (TB)]. Employing a [retrospective cohort study], the researchers compared the [time to TB diagnosis] in patients who initially received [gemifloxacin] for suspected pneumonia with those who received [other antibiotics]. Their findings reveal that [gemifloxacin may delay the diagnosis of TB] due to its [limited in vitro activity against Mycobacterium tuberculosis]. This discovery highlights the importance of [considering the potential for TB in patients with suspected pneumonia], especially in regions where [TB is prevalent].

The Potential Pitfalls of Gemifloxacin in TB Diagnosis

The study's key finding, [the delayed TB diagnosis in patients initially treated with gemifloxacin], highlights the importance of [clinical vigilance] when considering [gemifloxacin] for the treatment of pneumonia. It's like trying to find a hidden oasis in a vast desert—a seemingly harmless shortcut might lead you astray. In areas where [TB is endemic], [gemifloxacin should be used cautiously] and [alternative antibiotics] should be considered, especially if [the patient's clinical presentation is suggestive of TB].

Navigating the Diagnosis of TB

This research underscores the importance of [considering the possibility of TB] in patients with suspected pneumonia, particularly in regions where [TB is prevalent]. It's crucial to [obtain a thorough medical history and perform appropriate diagnostic tests] to [rule out TB] as a potential cause of [respiratory symptoms]. This approach can help ensure that [patients receive timely and appropriate treatment] and [prevent the spread of TB] within the community.

Dr.Camel's Conclusion

This research serves as a reminder that the fight against TB requires constant vigilance and a nuanced approach to antibiotic selection. It's like navigating a vast desert—one wrong turn could lead to a long and treacherous journey. By being aware of the potential pitfalls, we can ensure that patients receive the most effective treatment and that the spread of TB is contained.

Date :
  1. Date Completed 2013-09-09
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

23486643

DOI: Digital Object Identifier

PMC3594600

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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