Paper Details

  1. Home
  2. Paper Details

[Bacillus Calmette-Guerin maintenance treatment in non-invasive bladder tumors: 1 year follow-up results of multicenter URO-BCG-4 trial].

Author: , ColombelM, FantoniJ C, GalliotI, GuyL, IraniJ, Le GallS, PfisterC, RigaudJ, SaintF, SoulieM, StaermanF, WallerandH

Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Intravesical BCG instillations are the standard treatment for intermediate and high-risk non-muscle invasive bladder cancer. Maintenance therapy is recommended but often discontinued due to side effects. This study evaluated a new maintenance schedule with reduced BCG dose and fewer instillations per cycle.
Paper Details　
Original Abstract of the Article :
Intravesical instillations of BCG remains the gold standard for intermediate and high risk NMIBC management. Maintenance treatment is recommended, however, the frequency of side effects responsible for the discontinuation of maintenance therapy over four out of five patients before the third year su...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.purol.2012.12.010

データ提供：米国国立医学図書館（NLM）

Navigating the Desert of Bladder Cancer: Maintenance Treatment with BCG

Non-invasive bladder cancer, a formidable foe, requires careful management and treatment. This study delves into the world of Bacillus Calmette-Guerin (BCG) maintenance therapy for non-invasive bladder cancer, exploring potential approaches to optimize treatment. Think of BCG as a warrior in the desert, fighting to control the spread of cancer cells.

The researchers meticulously examined the effectiveness of BCG maintenance therapy, seeking to find the most effective and tolerable schedule for patients. They are looking for ways to minimize side effects and optimize the effectiveness of BCG therapy. It's like searching for a balance between fighting the enemy and minimizing collateral damage in the desert of bladder cancer.

The study found that a modified BCG maintenance schedule, involving fewer instillations and a reduced dose in the third cycle, showed promising results. This suggests that it might be possible to improve the tolerability of BCG treatment while maintaining its effectiveness. It's like finding a balance between fighting the enemy and minimizing collateral damage in the desert of bladder cancer.

The Importance of Optimizing BCG Therapy

This study highlights the importance of carefully evaluating and optimizing BCG maintenance therapy for non-invasive bladder cancer. It's like navigating the desert of treatment options, seeking the most effective and tolerable approach.

The Power of Research in Bladder Cancer Treatment

This study is a testament to the ongoing efforts to improve bladder cancer treatment. It's like venturing into the vast desert of research, seeking new solutions to combat this disease.

Dr.Camel's Conclusion

This study explores the effectiveness of BCG maintenance therapy for non-invasive bladder cancer, seeking to find a balance between fighting the cancer and minimizing side effects. It's like carefully navigating the desert of treatment options, aiming to find the most effective and tolerable approach.

Date :
  1. Date Completed 2013-09-30
  2. Date Revised 2013-04-02
Further Info :

Pubmed ID

23545009

DOI: Digital Object Identifier

10.1016/j.purol.2012.12.010

SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.