[Imatinib plasma levels in the management of cutaneous side effects induced by imatinib (Glivec®): 2 case reports].

Author: DaghfousRiadh, El AïdliSihem, GaïesEmna, KlouzAnis, LakhalMohamed, SahnounRim, SraïriSamia, TrabelsiSameh

Paper Details 
Original Abstract of the Article :
Imatinib, an antineoplastic drug used to treat certain cancers, has many side effects such as hematologic, neurologic or cutaneous toxicity. These toxicities seem to be due to a high imatinib plasmatic concentration and are frequently controlled by a discontinuation or a dosage reduction of the drug...See full text at original site
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引用元:
https://doi.org/10.1684/abc.2013.0795

データ提供:米国国立医学図書館(NLM)

Imatinib Plasma Levels and Cutaneous Side Effects

Imatinib is an antineoplastic drug used to treat certain cancers, but it can also cause a variety of side effects, including hematologic, neurologic, and cutaneous toxicity. These toxicities often result from high imatinib plasma concentrations and are frequently managed by reducing or discontinuing the drug. This case report explores the importance of monitoring imatinib plasma levels in patients experiencing cutaneous side effects. The authors present two cases where imatinib induced cutaneous side effects, highlighting the critical role of drug monitoring in such situations. By monitoring plasma levels, healthcare providers can determine if the levels are toxic and make informed decisions about adjusting the dosage or discontinuing the drug to minimize adverse effects.

The Importance of Drug Monitoring

This case report emphasizes the critical need for careful drug monitoring, particularly in patients receiving medications that can cause significant side effects. Regular monitoring of plasma levels can help identify potential toxicity and allow for timely adjustments in treatment to minimize adverse effects.

Living with Cancer: A Collaborative Effort

Navigating the challenges of cancer treatment requires a close collaboration between patients and their healthcare providers. Open communication, adherence to treatment plans, and regular follow-up appointments are essential. If you or someone you know is receiving cancer treatment, it's crucial to stay informed about the potential side effects of medications and seek guidance from healthcare professionals to address any concerns or manage adverse effects.

Dr.Camel's Conclusion

This case report underscores the importance of individualizing medical care and the critical role of drug monitoring in minimizing adverse effects. By carefully monitoring drug levels and adjusting treatment as needed, healthcare providers can help ensure the safety and well-being of patients receiving potentially toxic medications.

Date :
  1. Date Completed 2013-10-31
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

23587588

DOI: Digital Object Identifier

10.1684/abc.2013.0795

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SNS
PICO Info
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Languages

French

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