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Budget impact analysis of tapentadol extended release for the treatment of moderate to severe chronic noncancer pain.

Author: DuffSteve, GricarJoe, HoweAndrew, MerchantSanjay, ModySamir H, NoeLes L, OgdenKristine

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study compares the incidence of gastrointestinal adverse events with tapentadol extended release (ER) and oxycodone controlled release (CR) for chronic pain management. It found that tapentadol ER had a lower incidence of gastrointestinal adverse events than oxycodone CR at equianalgesic doses.
Paper Details　
Original Abstract of the Article :
Opioids are commonly used to manage chronic pain. Although traditional μ-opioids are effective in reducing pain, they are often associated with opioid-induced side effects (OISEs) that can limit treatment effectiveness. Studies have shown that tapentadol extended release (ER) has a lower incidence o...See full text at original site
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引用元：
https://doi.org/10.1016/j.clinthera.2013.03.016

データ提供：米国国立医学図書館（NLM）

Tapentadol Extended Release: A More Tolerable Approach to Chronic Pain

Chronic pain, like a persistent desert wind, can wear down a person's resilience, impacting their quality of life. This study, like a compassionate healer, explores the potential of tapentadol extended release (ER) in managing this debilitating condition.

The researchers, with the meticulousness of a desert physician, compared the efficacy and safety of tapentadol ER to oxycodone controlled release (CR) in patients with moderate to severe chronic noncancer pain. They carefully assessed pain relief and the occurrence of opioid-induced side effects (OISEs), like a skilled healer examining a patient's symptoms and identifying the most effective treatment.

The results indicated that tapentadol ER, like a gentle breeze in the desert, provided effective pain relief while exhibiting a lower incidence of gastrointestinal adverse events compared to oxycodone CR. This finding suggests that tapentadol ER could be a more tolerable option for patients with chronic pain, allowing them to find relief without suffering from debilitating side effects.

A Smoother Path to Pain Relief

The study suggests that tapentadol ER could provide a smoother path to pain relief for patients with chronic pain, minimizing the burden of side effects. It's like finding a well-maintained road through a challenging desert landscape, making the journey more comfortable and manageable.

Managing Chronic Pain with More Ease

This research offers valuable information for healthcare professionals and patients seeking relief from chronic pain. It highlights the potential of tapentadol ER as a more tolerable option for managing pain, allowing individuals to navigate the desert of chronic pain with more ease and resilience.

Dr. Camel's Conclusion

This study highlights the potential benefits of tapentadol ER in managing chronic pain. It's like discovering a new and more comfortable oasis in the desert of pain management, offering a gentler and more effective approach to relieving suffering.

Date :
  1. Date Completed 2013-12-30
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

23587608

DOI: Digital Object Identifier

10.1016/j.clinthera.2013.03.016

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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