Comparison of the analgesic effects of dronabinol and smoked marijuana in daily marijuana smokers.

Author: ComerSandra D, CooperZiva D, HaneyMargaret

Paper Details 
Original Abstract of the Article :
Recent studies have demonstrated the therapeutic potential of cannabinoids to treat pain, yet none have compared the analgesic effectiveness of smoked marijuana to orally administered Δ(9)-tetrahydrocannabinol (THC; dronabinol). This randomized, placebo-controlled, double-dummy, double-blind study c...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746706/

データ提供:米国国立医学図書館(NLM)

Smoked Marijuana vs. Dronabinol: A Pain Relief Showdown

The quest for effective pain relief is an ongoing pursuit in medicine. This study, like a skilled alchemist experimenting with different compounds, compares the analgesic effects of smoked marijuana and dronabinol, a synthetic form of THC, in individuals who regularly use marijuana. The research, using a rigorous, double-blind, placebo-controlled design, explores the effectiveness of these two methods in reducing pain, examining both the intensity and duration of their analgesic effects.

The Analgesic Race

The results, like a desert race, reveal a fascinating comparison. The study found that both smoked marijuana and dronabinol effectively reduced pain sensitivity and increased pain tolerance. However, dronabinol produced a longer-lasting analgesic effect than smoked marijuana. The researchers also found that both methods produced subjective feelings of intoxication, but these effects were more pronounced with smoked marijuana.

Weighing the Benefits and Risks

This study underscores the importance of considering both the potential benefits and risks of different pain management strategies. While both smoked marijuana and dronabinol offer potential pain relief, their distinct effects and associated risks require careful consideration. The study's findings provide valuable insights for guiding clinical decision-making and ultimately ensuring the most effective and safe treatment approach for individual patients.

Dr. Camel's Conclusion

Like a camel seeking out the most nourishing oasis, researchers are always searching for the most effective ways to alleviate pain. This study, like a well-mapped desert trail, compares the analgesic effects of smoked marijuana and dronabinol. While both methods offer potential pain relief, their distinct effects and risks require careful consideration. Ultimately, the choice of treatment should be tailored to individual needs and preferences, ensuring the best possible outcome for the patient.

Date :
  1. Date Completed 2014-03-24
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

23609132

DOI: Digital Object Identifier

PMC3746706

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Languages

English

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