Dual orexin receptor antagonists - promising agents in the treatment of sleep disorders.

Author: CzajkowskaBeata, KrzystanekMarek, LaprayDamien, MarkowskiGrzegorz, PałaszArtur, PeyronChristelle, Rojczyk-GołębiewskaEwa, SkowronekRafał, WiaderkiewiczRyszard

Paper Details 
Original Abstract of the Article :
Insomnia is a serious medical and social problem, its prevalence in the general population ranges from 9 to 35% depending on the country and assessment method. Often, patients are subject to inappropriate and therefore dangerous pharmacotherapies that include prolonged administration of hypnotic dru...See full text at original site
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引用元:
https://doi.org/10.1017/S1461145713000552

データ提供:米国国立医学図書館(NLM)

Dual Orexin Receptor Antagonists: A New Oasis in the Desert of Insomnia

The [treatment of insomnia] is a challenging landscape, with many patients struggling to find effective and safe solutions. This research explores the potential of [dual orexin receptor antagonists] as a [novel treatment option] for [insomnia]. The authors discuss the [limitations of current treatments], such as [hypnotic drugs and benzodiazepines], and highlight the [unique advantages] of [dual orexin receptor antagonists]. This review delves into the [role of orexin-expressing neurons] in [regulating sleep-wake cycles] and emphasizes the potential of [dual orexin receptor antagonists] to [improve sleep quality] without the [undesirable side effects] associated with traditional medications.

A New Path Through the Desert of Insomnia: Dual Orexin Receptor Antagonists

This research suggests that [dual orexin receptor antagonists] could offer a [more effective and safer approach] to [treating insomnia]. The [unique mechanism of action] of these drugs, targeting [orexin receptors], sets them apart from traditional treatments and may lead to [improved sleep architecture] and [reduced side effects]. This research offers a promising new direction for [insomnia management].

A Camel's Perspective on Orexin Receptor Antagonists: A Restful Oasis

The desert of [insomnia] can be a harsh and unforgiving place, leaving many weary travelers searching for a peaceful night's rest. This research suggests that [dual orexin receptor antagonists] could offer a new oasis of respite, providing a more effective and safer solution for [insomnia]. The potential of these drugs to [improve sleep quality] without the [undesirable side effects] of traditional treatments is a significant step forward in the pursuit of [better sleep].

Dr. Camel's Conclusion

This research sheds light on a promising new approach to treating insomnia. Dual orexin receptor antagonists offer a potential alternative to traditional medications, with the potential to improve sleep quality and reduce side effects. The exploration of new treatments for insomnia is a testament to the ongoing efforts to find solutions in the desert of sleep disorders.

Date :
  1. Date Completed 2014-11-28
  2. Date Revised 2016-10-20
Further Info :

Pubmed ID

23702225

DOI: Digital Object Identifier

10.1017/S1461145713000552

Related Literature

SNS
PICO Info
in preparation
Languages

English

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