Efficacy and safety of pentavalent rotavirus vaccine in Japan: a randomized, double-blind, placebo-controlled, multicenter trial.

Author: BrownMichelle L, IwataSatoshi, KoizumiYoshitugu, KurokiHaruo, LawrenceJody, MoritaYasuyuki, NakataShuji, SchödelFlorian, ShizuyaToshiyuki, TanakaYoshiyuki, UkaeSusumu

Paper Details 
Original Abstract of the Article :
Rotavirus is the most common cause of severe gastroenteritis in children under 5 y of age. Estimates of disease burden in Japan suggest that between 26,500 and 78,000 children in this age group need hospitalization each year, resulting in a direct medical cost of 10 to 24 billion Yen. Since being in...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906258/

データ提供:米国国立医学図書館(NLM)

Rotavirus Vaccine: A Powerful Weapon Against Gastroenteritis

Rotavirus, a formidable foe in the desert of childhood illnesses, causes severe gastroenteritis, often leading to hospitalization. This study, like a valiant knight armed with a potent shield, evaluates the efficacy and safety of a pentavalent rotavirus vaccine (RV5) in preventing RVGE in Japanese infants. The researchers, like warriors battling against disease, discovered that RV5 significantly reduced the incidence of RVGE, providing much-needed protection for vulnerable infants.

RV5: A Promising Tool for Preventing Rotavirus Gastroenteritis

This study demonstrates that RV5 is a highly effective and safe vaccine against rotavirus gastroenteritis. The results, like a triumphant victory over a formidable enemy, show a significant reduction in the incidence of RVGE, especially in preventing severe cases. This is a significant development in the fight against this common and debilitating childhood illness.

Protecting Infants from Rotavirus

This study provides a compelling argument for the widespread use of RV5 in Japan, and potentially other countries as well. By protecting infants from the ravages of rotavirus, like building a sturdy fortress against a relentless desert storm, we can reduce the burden of this disease and improve the health and well-being of children. This is a testament to the power of vaccination in safeguarding the health of future generations.

Dr.Camel's Conclusion

This research, like a caravan carrying valuable treasures, delivers a powerful weapon against rotavirus gastroenteritis. The study highlights the efficacy and safety of RV5, paving the way for a healthier future for infants. This discovery is a triumph in the fight against childhood diseases, offering hope and protection for the next generation.

Date :
  1. Date Completed 2014-05-06
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

23732903

DOI: Digital Object Identifier

PMC3906258

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.