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Dalfampridine: review of its efficacy in improving gait in patients with multiple sclerosis.

Author: EtemadifarM, MaghziA H, MinagarA, SahraianM A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Dalfampridine, a potassium channel blocker, is a medication used to treat multiple sclerosis. It improves walking ability in MS patients by enhancing conduction in demyelinated axons.
Paper Details　
Original Abstract of the Article :
Multiple sclerosis (MS) is a progressive immune-mediated neurodegenerative disease of human central nervous system (CNS), which causes irreversible disability in young adults. The cause and cure for MS remain unknown. Pathophysiology of MS includes two arms: inflammatory demyelination and neurodegen...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663610/

データ提供：米国国立医学図書館（NLM）

Restoring Movement in Multiple Sclerosis: The Role of Dalfampridine

Multiple sclerosis (MS) is a complex neurodegenerative disease, often leading to debilitating mobility challenges. This review examines the potential of dalfampridine (4-aminopyridine) as a treatment for gait impairment in MS patients. The authors highlight dalfampridine's mechanism of action, its role in enhancing conduction in demyelinated axons, and its efficacy in improving walking ability.

A Path Through the Desert: Dalfampridine for Gait Impairment in MS

Dalfampridine offers a beacon of hope for those struggling with gait impairment caused by MS. By enhancing conduction in demyelinated axons, dalfampridine can help improve mobility and restore independence. This research provides a valuable overview of the potential benefits and limitations of this medication.

Living with MS: Strategies for Maintaining Mobility

Managing the challenges of MS requires a multifaceted approach, including medications, rehabilitation therapies, and lifestyle modifications. This research highlights the importance of exploring all available treatment options to optimize mobility and quality of life.

Dr. Camel's Conclusion

Dalfampridine provides a potential path through the desert of MS-related gait impairment. This review provides a valuable summary of the current understanding of dalfampridine's role in treating MS, offering hope for improved mobility and independence for those living with this complex condition.
Date :
  1. Date Completed 2013-07-17
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

23861641

DOI: Digital Object Identifier

PMC3663610

Related Literature

Article Analysis
・Side Effects of dalfampridine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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