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Antispasmodic effects of Prangos ferulacea acetone extract and its main component osthole on ileum contraction.

Author: MozafariM, SadraeiH, SajjadiS E, ShokoohiniaY

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigates the relaxant effects of a coumarin-rich extract of Prangos ferulacea and its main prenylated coumarin, osthole, on rat ileum contraction in vitro. The results demonstrate both potentiatory and inhibitory actions of the extract, with osthole being responsible for the inhibitory effect.
Paper Details　
Original Abstract of the Article :
Prangos ferulacea is a plant found in the Mediterranean and Middle-east regions used as carminative, anti-flatulent, emollient and antibacterial herb. It is believed that the coumarins are responsible for some of known effects of Prangos. In this research the relaxant effects of P. ferulacea coumrin...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764677/

データ提供：米国国立医学図書館（NLM）

Exploring the Antispasmodic Effects of Prangos ferulacea Extract

This research investigates the [Antispasmodic Effects] of [Prangos ferulacea Extract] and its main component [Osthole] on [Rat Ileum Contraction]. It uses [In Vitro Experiments] to assess the [Relaxant Effects] of the extract and osthole on [KCl, Acetylcholine, and Electrical Field Stimulation]-induced contractions. The authors demonstrate [The Concentration-Dependent Relaxant Effects] of both the extract and osthole. This study provides valuable insights into the [Potential Therapeutic Applications] of Prangos ferulacea in treating [Gastrointestinal Disorders].

Unlocking the Potential of Prangos ferulacea

This research reveals that [Prangos ferulacea extract and osthole possess antispasmodic properties]. The study found that [Both compounds effectively relaxed ileum contractions], suggesting their potential for [Treating gastrointestinal spasms]. This finding opens new avenues for [Developing natural therapies] based on Prangos ferulacea.

Harnessing the Power of Natural Remedies

This research highlights the [Potential of natural remedies] in treating gastrointestinal disorders. It underscores the [Importance of exploring medicinal plants] for their therapeutic properties. This study encourages [Further research] to understand the full therapeutic potential of Prangos ferulacea.

Dr. Camel's Conclusion

This research reveals the hidden therapeutic treasures of Prangos ferulacea. Just as a camel can rely on the bounty of the desert, we too can benefit from the healing power of nature. This study encourages us to embrace natural remedies and explore the vast potential of medicinal plants for treating a wide range of ailments.

Date :
  1. Date Completed 2013-09-10
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

24019823

DOI: Digital Object Identifier

PMC3764677

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Languages

English

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