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Dalfampridine improves walking speed, walking endurance, and community participation in veterans with multiple sclerosis: a longitudinal cohort study.

Author: CameronMichelle H, FitzpatrickMary, ManningJane, MurchisonCharles, OversShannon, WhithamRuth

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Dalfampridine extended release (ER) was associated with short-term improvements in walking speed and community participation and sustained improvements in walking endurance and self-perceived impact of MS on walking for one year.
Paper Details　
Original Abstract of the Article :
BACKGROUND: In short-term trials, dalfampridine extended release (ER) improves walking in people with multiple sclerosis (MS). The tolerability and effects of dalfampridine-ER in clinical practice have not been reported. OBJECTIVES: The objective of this paper is to determine the clinical tolerabil...See full text at original site
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引用元：
https://doi.org/10.1177/1352458513507356

データ提供：米国国立医学図書館（NLM）

Dalfampridine: A Promising Treatment for Multiple Sclerosis

Multiple sclerosis (MS) is a debilitating disease that affects the nervous system. This research explores the long-term effects of dalfampridine extended release (ER) on walking ability and community participation in veterans with MS. The researchers conducted a longitudinal cohort study, tracking the progress of patients over a one-year period.

They found that dalfampridine-ER was associated with significant improvements in walking speed, walking endurance, and community participation, suggesting its potential for improving the quality of life for individuals with MS.

The Importance of Long-Term Studies in MS Research

This study demonstrates the importance of conducting long-term research to evaluate the sustained benefits of treatments for chronic conditions like MS. By tracking patients over time, researchers can gain a more complete understanding of the long-term effects of therapies and identify any potential challenges or limitations.

The Importance of Mobility in MS Management

This research highlights the importance of addressing mobility issues in MS management. By improving walking ability, dalfampridine-ER can enhance the independence and quality of life of individuals with MS.

Dr. Camel's Conclusion

This research is like a refreshing oasis in the desert of MS research, offering hope for improved mobility and quality of life for those affected by this challenging condition.

Date :
  1. Date Completed 2015-03-30
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

24099749

DOI: Digital Object Identifier

10.1177/1352458513507356

Related Literature

Article Analysis
・Effects of dalfampridine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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