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Effects of early inhaled epoprostenol therapy on pulmonary artery pressure and blood loss during LVAD placement.

Author: AhmadHasan B, BlumFranziska E, DurieuxMarcel E, GrovesDanja S, HuffmyerJulie L, KennedyJamie L W, KernJohn A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study evaluated the impact of early initiation of epoprostenol administration during LVAD placement on pulmonary artery pressures, use of vasoactive drugs, and blood loss. Epoprostenol, an inhaled prostacyclin, selectively dilates the pulmonary vasculature, but also inhibits platelet aggregation. Early epoprostenol administration may impact pulmonary artery pressures and blood loss during LVAD placement.
Paper Details　
Original Abstract of the Article :
Several strategies have been used to reduce the incidence of right ventricular failure after left ventricular assist device (LVAD) placement, including pulmonary vasodilation. The inhaled prostacyclin, epoprostenol, selectively dilates the pulmonary vasculature of ventilated areas of the lung, but a...See full text at original site
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引用元：
https://doi.org/10.1053/j.jvca.2013.05.028

データ提供：米国国立医学図書館（NLM）

Minimizing Complications During LVAD Placement: The Role of Inhaled Epoprostenol

The field of [cardiac surgery] is constantly striving to improve outcomes for patients undergoing [left ventricular assist device (LVAD) placement]. This study investigated the impact of early [inhaled epoprostenol] administration on [pulmonary artery pressure], [vasoactive drug] use, and [blood loss] during LVAD placement. The researchers aimed to evaluate the potential benefits of epoprostenol in mitigating complications associated with LVAD placement.

Epoprostenol: A Promising Approach for LVAD Placement

The study suggests that early initiation of inhaled epoprostenol during LVAD placement may reduce pulmonary artery pressures and blood loss. The findings indicate that epoprostenol may be a valuable tool for managing complications associated with LVAD placement, particularly in high-risk patients. This research highlights the importance of utilizing pharmacologic interventions to minimize surgical complications and improve patient outcomes.

Improving Outcomes in Cardiac Surgery

For individuals undergoing cardiac surgery, particularly LVAD placement, this research underscores the importance of exploring innovative strategies to minimize complications. The study’s findings highlight the potential of inhaled epoprostenol as a valuable adjunct to standard surgical procedures. This research contributes to the ongoing efforts to improve the safety and effectiveness of cardiac surgery.

Dr. Camel's Conclusion

This study reminds us that even in the complex and demanding world of cardiac surgery, there are oases of innovation and progress. Epoprostenol emerges as a potential tool to help navigate the challenging landscape of LVAD placement, minimizing complications and improving outcomes for patients. The research highlights the importance of ongoing investigation and refinement of surgical techniques and pharmacologic interventions, ultimately leading to better care and improved lives for those undergoing cardiac surgery.

Date :
  1. Date Completed 2015-01-20
  2. Date Revised 2014-06-11
Further Info :

Pubmed ID

24103713

DOI: Digital Object Identifier

10.1053/j.jvca.2013.05.028

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・Effects of epoprostenol
SNS
PICO Info
in preparation
Languages

English

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