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Comparative study of actinic keratosis treatment with 3% diclofenac sodium and 5% 5-fluorouracil.

Author: DornellesSérgio Ivan Torres, FrantzGabriela de Oliveira, SegattoMajoriê Mergen, SilveiraVera Bauer

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A randomized controlled trial of 28 patients with actinic keratosis found that 5-Fluorouracil was more effective than diclofenac sodium in reducing the number of lesions. However, 5-Fluorouracil was associated with lower tolerability, with more erythema, edema, crusts, and itching.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Actinic keratosis is a frequent lesion which occurs in sunlight exposed areas. Diclofenac sodium and 5-Fluorouracil are effective, non-invasive and easy-to-apply topical treatment options. OBJECTIVES: To assess and compare the effectiveness of 3% diclofenac sodium associated with 2.5% h...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798349/

データ提供：米国国立医学図書館（NLM）

Actinic Keratosis: Comparing Treatment Options

Actinic keratosis is a precancerous skin condition often caused by excessive sun exposure. This study compares the effectiveness of two topical treatments for actinic keratosis: 3% diclofenac sodium and 5% 5-fluorouracil. This research helps clinicians make informed decisions regarding the best treatment option for their patients.

5-Fluorouracil: A More Effective Choice

The study reveals that 5-fluorouracil was more effective in reducing actinic keratosis lesions compared to diclofenac sodium. This finding is significant for clinicians as it provides evidence to guide their treatment choices for actinic keratosis.

Navigating the Desert of Skin Cancer

This research is like a compass, guiding us toward the most effective treatment options for actinic keratosis. It's a reminder that careful consideration of treatment options is essential when dealing with skin cancer prevention.

Dr.Camel's Conclusion

This research sheds light on the effectiveness of different topical treatments for actinic keratosis. It's like a guidebook for navigating the desert of skin cancer, helping us choose the best treatment options for our patients.

Date :
  1. Date Completed 2014-04-22
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

24173178

DOI: Digital Object Identifier

PMC3798349

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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