Comparison of the antibacterial effects of matrica & Persica™ and chlorhexidine gluconate mouthwashes in mechanically ventilated ICU patients: a double blind randomized clinical trial.

Author: Darvishi KhezriHadi, GorjiHeidari, Haidari GorjiMohammad Ali, MoradAli

Paper Details 
Original Abstract of the Article :
BACKGROUND: Accumulation of bacteria in the pharynx is one of the risk factors of pneumonia due to ventilation. One of the methods of prevention from accumulation of bacteria in the pharynx is the use of oral solutions. Chlorhexidine is considered as the gold standard, but it has various side effect...See full text at original site
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引用元:
https://doi.org/10.4067/S0716-10182013000400003

データ提供:米国国立医学図書館(NLM)

Antibacterial Mouthwashes: Fighting Bacteria in Ventilated Patients

Mechanical ventilation, a life-saving intervention for critically ill patients, can also create a breeding ground for bacteria in the pharynx. This research compares the antibacterial effects of different mouthwashes in mechanically ventilated intensive care unit (ICU) patients, a critical quest to prevent ventilator-associated pneumonia (VAP). The study, a double-blind randomized clinical trial, investigated the effectiveness of chlorhexidine gluconate, a standard antibacterial agent, and two herbal mouthwashes, Matrica® and PersicaTM, in reducing bacterial colonization in the pharynx. The findings offer insights into the potential for alternative mouthwash options to combat VAP.

Herbal Mouthwashes: Potential Alternatives for VAP Prevention

The study revealed that both herbal mouthwashes, Matrica® and PersicaTM, demonstrated significant antibacterial effects against Staphylococcus aureus and Streptococcus pneumoniae, comparable to chlorhexidine gluconate. These findings suggest that these herbal mouthwashes could offer a potential alternative to chlorhexidine for VAP prevention, a promising development in the fight against this serious complication. Further research is needed to confirm these findings and to assess the long-term efficacy and safety of these herbal mouthwashes in a clinical setting.

Navigating the Desert of VAP Prevention: Exploring New Options

The study's findings highlight the potential of herbal mouthwashes as valuable tools for preventing VAP in mechanically ventilated ICU patients. These alternative options could offer benefits in terms of reduced side effects and improved patient compliance. Further research is needed to establish the optimal use of these herbal mouthwashes and to ensure their safety and efficacy in a clinical setting. As we continue to explore the vast desert of VAP prevention strategies, herbal mouthwashes may offer a promising oasis, providing new avenues for combating this serious complication.

Dr. Camel's Conclusion

The quest for effective VAP prevention strategies continues, and herbal mouthwashes may offer a promising oasis in this vast desert. Further research is needed to confirm their effectiveness and safety in a clinical setting, but these findings offer hope for new and potentially more patient-friendly options for preventing this serious complication.

Date :
  1. Date Completed 2014-02-04
  2. Date Revised 2013-11-19
Further Info :

Pubmed ID

24248104

DOI: Digital Object Identifier

10.4067/S0716-10182013000400003

Related Literature

SNS
PICO Info
in preparation
Languages

English

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