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The adverse effects profile of levetiracetam in epilepsy: a more detailed look.

Author: DixonPete, HuttonJane L, MarsonAnthony G, MbizvoGashirai K

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Levetiracetam is a commonly used medication for epilepsy, but its full adverse effects profile is still under investigation. This review examines common and uncommon adverse effects of levetiracetam, including somnolence, headache, asthenia, accidental injury, dizziness, infection, pharyngitis, pain, rhinitis, abdominal pain, flu syndrome, vomiting, diarrhea, convulsion, nausea, increased cough, anorexia, upper respiratory tract infection, hostility, personality disorder, urinary tract infection, nervousness, depression, aggression, back pain, agitation, emotional liability, psychomotor hyperactivity, pyrexia, rash, ECG abnormalities, decreased appetite, nasal congestion, irritability, abnormal behavior, epistaxis, insomnia, altered mood, anxiety, bloody urine, diplopia, dissociation, memory impairment, pruritis, increased appetite, acne, and stomach discomfort. Somnolence and infection were the only significantly associated adverse effects. The review updates the adverse effects profile data on levetiracetam by empirically reporting common and uncommon effects and analyzing their relative importance statistically.
Paper Details　
Original Abstract of the Article :
The adverse effects profile of levetiracetam in epilepsy is still being fully described. We recently published a Cochrane Review evaluating the effectiveness of levetiracetam, added on to usual care, in treating drug-resistant focal epilepsy. The five most common adverse effects were reported and an...See full text at original site
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引用元：
https://doi.org/10.3109/00207454.2013.866951

データ提供：米国国立医学図書館（NLM）

A Deeper Dive into the Adverse Effects Profile of Levetiracetam in Epilepsy

This research delves into the world of epilepsy treatment, specifically focusing on the adverse effects profile of levetiracetam, a commonly prescribed antiepileptic drug. The authors expand upon a previous Cochrane review, providing a more detailed analysis of the common and less common adverse effects associated with levetiracetam use. They analyze a comprehensive range of adverse effects, including somnolence, headache, asthenia, accidental injury, dizziness, and various infections. This study aims to provide a more complete understanding of the potential risks and benefits of levetiracetam treatment for individuals with epilepsy.

Understanding the Potential Side Effects of Levetiracetam

The research findings reveal a wide range of adverse effects associated with levetiracetam, with somnolence and infection being the most significant. The study also highlights the importance of considering the potential variations in adverse effects profile between adults and children. These insights are crucial for clinicians in making informed decisions regarding levetiracetam treatment, ensuring that patients receive safe and effective care.

Navigating the Landscape of Epilepsy Treatment

This research emphasizes the importance of weighing the potential benefits and risks of different epilepsy medications. It underscores the need for careful monitoring and individualized treatment approaches to minimize the occurrence of adverse effects. This study serves as a valuable resource for clinicians and patients, enabling them to navigate the complex landscape of epilepsy treatment with greater understanding and awareness.

Dr.Camel's Conclusion

Just like a desert traveler seeking refuge from the scorching sun, individuals with epilepsy often seek relief from their debilitating seizures. This research provides valuable insights into the potential side effects of levetiracetam, helping clinicians and patients make informed decisions about treatment options. It reminds us that the journey to managing epilepsy is not always smooth, but with knowledge and careful consideration, we can find pathways to relief and improved well-being.
Date :
  1. Date Completed 2015-04-17
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

24256446

DOI: Digital Object Identifier

10.3109/00207454.2013.866951

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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