Early nonresponse determined by the clinical global impressions scale predicts poorer outcomes in youth with schizophrenia spectrum disorders naturalistically treated with second-generation antipsychotics.

Author: Al-JadiriAseel, CarbonMaren, ChekuriRaja, CorrellChristoph U, Fink-JensenAnders, JeppesenPia, KaneJohn M, KapoorSandeep, KishimotoTaishiro, PagsbergAnne K, Stentebjerg-OlesenMarie

Paper Details 
Original Abstract of the Article :
The use of early response/nonresponse (ER/ENR) to antipsychotics as a predictor for ultimate response/nonresponse (UR/UNR) may help decrease inefficacious treatment continuation. However, data have been limited to adults, and ER/ENR has only been determined using time-consuming psychopathology ratin...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870605/

データ提供:米国国立医学図書館(NLM)

Early Nonresponse in Youth with Schizophrenia Spectrum Disorders

The journey to effectively manage schizophrenia spectrum disorders (SSD) can be long and arduous. Mental health professionals are constantly seeking better ways to predict treatment outcomes and optimize patient care. This study dives deep into the early phases of treatment to understand if early nonresponse to antipsychotics can predict long-term outcomes in youth with SSD.

Early Nonresponse as a Predictor of Outcome

The authors used the Clinical Global Impressions-Improvement (CGI-I) scale, a commonly used tool in mental health assessments. They found that early improvement on the CGI-I scale was a significant predictor of ultimate response to antipsychotics. In simpler terms, those who showed early improvement on the scale were more likely to respond well to treatment in the long run. This finding is significant as it provides a valuable tool for identifying patients who may need more intensive monitoring or alternative treatment strategies.

Early Intervention: A Key to Success

This research underscores the importance of early intervention in SSD treatment. By carefully monitoring a patient's response to medication in the early stages, mental health professionals can tailor treatment plans to maximize their effectiveness and minimize the risk of delayed or ineffective treatment. This is akin to a camel navigating the desert, using early signs of trouble to adjust its path and ensure a smoother journey.

Dr. Camel's Conclusion

This study is a valuable contribution to the field of SSD treatment. It emphasizes the power of early intervention and highlights the significance of tools like the CGI-I scale in predicting treatment outcomes. Like a wise camel recognizing the signs of an approaching sandstorm, we can use this knowledge to better guide our patients toward a brighter future.

Date :
  1. Date Completed 2014-10-06
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

24266529

DOI: Digital Object Identifier

PMC3870605

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.