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Statin-induced Myopathy.

Author: FitzgeraldKara, HarborCathryn, RedmondElizabeth

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.

Overview

Statin therapy for cholesterol reduction is a common treatment for heart disease, but it can also cause side effects like myalgia and mitochondrial myopathy. This case report suggests that statin-induced mitochondrial myopathy can occur despite normal serum creatine kinase levels.
Paper Details　
Original Abstract of the Article :
Heart disease (HD) is the number one killer in the United States.(1) In 2006, the direct and indirect costs associated with cardiovascular disease in the United States were estimated at 400 billion dollars.(2) Statin therapy for cholesterol reduction is a mainstay intervention for cardiovascular dis...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833493/

データ提供：米国国立医学図書館（NLM）

Statins and Muscle Pain: A Complex Relationship

The field of cardiology focuses on the prevention and management of heart disease, often relying on statins to lower cholesterol levels. This research explores the potential side effect of statin therapy, specifically muscle pain or myopathy. The study reviews the literature on statin-induced myopathy, highlighting the link between statin use and mitochondrial dysfunction. The researchers suggest that statin-induced myopathy may be associated with CoQ10 depletion, a crucial component of mitochondrial energy production.

Statins and Mitochondrial Health

The study highlights the potential impact of statins on mitochondrial health, suggesting that statin-induced myopathy may result from CoQ10 depletion. This information emphasizes the importance of monitoring patients for potential side effects and considering the potential risks and benefits of statin therapy, especially in individuals with pre-existing mitochondrial dysfunction.

Maintaining Mitochondrial Health

Maintaining mitochondrial health is crucial for overall well-being. Engaging in regular exercise, consuming a balanced diet rich in antioxidants, and avoiding excessive alcohol consumption can help support mitochondrial function. Consulting a healthcare professional to address any concerns regarding statin therapy or mitochondrial health is essential for receiving appropriate guidance and care.

Dr.Camel's Conclusion

Just as a desert traveler must carefully manage their resources, statin therapy requires careful consideration and monitoring. Understanding the potential impact on mitochondrial health can help us make informed decisions about medication and prioritize overall well-being.

Date :
  1. Date Completed 2013-11-26
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

24278816

DOI: Digital Object Identifier

PMC3833493

SNS
PICO Info
in preparation
Languages

English

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