The subjective psychoactive effects of oral dronabinol studied in a randomized, controlled crossover clinical trial for pain.

Author: EdwardsRobert R, IssaMohammed A, JamisonRobert N, MichnaEdward, NarangSanjeet, PenetarDavid M, WasanAjay D

Paper Details 
Original Abstract of the Article :
Many cannabinoid medications are approved in North America or in phase III trials, such as dronabinol, nabilone, or nabiximols. Little is known about their subjective psychoactive effects when used for pain management. We hypothesized that when used for pain, dronabinol has psychoactive effects in a...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/24281276

データ提供:米国国立医学図書館(NLM)

Dronabinol: Exploring the Psychoactive Effects in Pain Management

Cannabis-based medications are gaining popularity in the treatment of various conditions, like finding a new path through a vast desert landscape. This study examines the subjective psychoactive effects of dronabinol, a synthetic cannabinoid, when used for pain management. The researchers are like skilled explorers, carefully navigating the terrain of pain management and seeking to understand the subtle effects of these medications.

Navigating the Effects: Understanding the Subjective Experience

This study investigates the subjective psychoactive effects of dronabinol, highlighting the importance of understanding the patient's experience when using cannabinoid-based medications. The researchers found that dronabinol had psychoactive effects in a dose-response relationship, suggesting that the intensity of the effects depends on the amount of medication taken. This is like understanding the different levels of intensity in a desert storm, where the strength of the wind and the amount of sand blown can vary significantly.

A Balancing Act: Finding the Right Dose

This research underscores the importance of finding the right dose of dronabinol to balance pain relief with potential psychoactive effects, much like adjusting the course of a camel caravan through a shifting desert landscape. The study's findings highlight the need for careful monitoring and titration of dronabinol to achieve the optimal balance between pain relief and manageable psychoactive effects, ensuring that the journey is as comfortable and effective as possible.

Dr. Camel's Conclusion

Dronabinol is a potential tool for pain management, but its psychoactive effects must be carefully considered. It's like navigating a desert with shifting sands, where careful planning and adjustments are essential to avoid potential hazards. This research is a reminder that even in the face of seemingly promising treatments, there are always potential risks and considerations to weigh. It's like discovering a hidden oasis in the desert, a source of healing and hope that can sustain us on our journey.

Date :
  1. Date Completed 2014-12-16
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

24281276

DOI: Digital Object Identifier

NIHMS541723

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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