Evaluation of the effects of anti-motion sickness drugs on subjective sleepiness and cognitive performance of healthy males.

Author: PattynN, Van de HeyningP H, WeertsA P, WuytsF L

Paper Details 
Original Abstract of the Article :
This study aimed to investigate the clinical and cognitive side effects of baclofen (10 mg), meclizine (25 mg), dimenhydrinate (40 mg) plus cinnarizine (25 mg) and promethazine (25 mg) plus d-amphetamine (10 mg). The study had a double-blind, placebo controlled, repeated measures design and was cond...See full text at original site
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引用元:
https://doi.org/10.1177/0269881113516201

データ提供:米国国立医学図書館(NLM)

Navigating the Effects of Anti-Motion Sickness Drugs

The study focuses on the effects of anti-motion sickness drugs on sleepiness and cognitive performance, a critical area of research in the realm of pharmaceutical science. The authors employ a double-blind, placebo-controlled, repeated measures design to investigate the effects of baclofen, meclizine, dimenhydrinate plus cinnarizine, and promethazine plus d-amphetamine on healthy male volunteers. The study utilizes a comprehensive battery of tests, including the psychomotor vigilance test, Sternberg working memory task, implicit memory test, and automated Operation Span (Ospan) task, to assess cognitive function and sleepiness. The authors meticulously analyze the effects of each drug on mood, adverse effects, and cognitive performance, providing valuable insights into the potential trade-offs associated with these medications. This research underscores the need for a careful assessment of both the benefits and drawbacks of anti-motion sickness drugs, particularly in terms of their impact on sleepiness and cognitive function. The authors' findings highlight the importance of individualizing treatment strategies, taking into account the specific needs and characteristics of each patient. The study's findings offer valuable guidance for clinicians in optimizing the use of these drugs, ultimately enhancing patient care.

Balancing Benefits and Drawbacks: A Journey Through the Mind

This research underscores the complex relationship between medication and cognitive function. Just as a desert traveler must carefully choose their path to avoid treacherous dunes, so too must we navigate the potential side effects of anti-motion sickness drugs. The study's findings show that some drugs, like meclizine, can impair short-term memory, while others, like baclofen, may negatively affect working memory. This highlights the importance of understanding the individual effects of each drug and considering the potential trade-offs before prescribing them. By carefully assessing the risks and benefits, we can make informed decisions that prioritize patient well-being.

Cognitive Function: A Dance with the Sands of Time

The study's findings emphasize the importance of maintaining cognitive function, particularly when considering the use of anti-motion sickness drugs. Just as the shifting sands of the desert can obscure our path, so too can impaired cognitive function hinder our ability to navigate the complexities of daily life. By being aware of the potential effects of these medications, we can adopt proactive measures to minimize their impact. This includes staying mindful of our cognitive capabilities, engaging in activities that promote brain health, and seeking professional guidance when necessary.

Dr.Camel's Conclusion

This study serves as a reminder that even seemingly benign medications can have unexpected effects on our cognitive function. As we venture through life's journey, we must be mindful of the subtle shifts that can impact our mental clarity. This research encourages us to approach medication with a discerning eye, always seeking a balance between the benefits and potential drawbacks.

Date :
  1. Date Completed 2018-01-16
  2. Date Revised 2018-01-16
Further Info :

Pubmed ID

24346808

DOI: Digital Object Identifier

10.1177/0269881113516201

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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