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Lansoprazole-induced hypomagnesaemia.

Author: FellowsIan Wilfred, KrupaLukasz Zbigniew

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.

Overview

This case report highlights the importance of considering hypomagnesaemia as a possible side effect of long-term proton pump inhibitor (PPI) therapy. A 73-year-old woman experienced supraventricular tachycardia due to hypomagnesaemia while using lansoprazole. Her arrhythmia resolved after intravenous magnesium replenishment and stopping her PPI. This case underscores the importance of checking serum magnesium concentrations in patients on PPIs, especially those who are unwell or present with arrhythmia.
Paper Details　
Original Abstract of the Article :
The introduction of proton pump inhibitors (PPIs) in the late 1980s optimised the medical treatment of acid-related disorders. They are potent medications and have a good safety profile. However, long-term therapy with PPIs may carry undesired side effects, one of which is hypomagnesaemia. This enti...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903331/

データ提供：米国国立医学図書館（NLM）

The Hidden Side Effects of Proton Pump Inhibitors: Hypomagnesaemia

Proton pump inhibitors (PPIs), widely used to treat acid-related disorders, have revolutionized the management of these conditions. However, their long-term use can have unexpected consequences, including hypomagnesaemia, a condition characterized by low magnesium levels. This case report presents a 73-year-old woman who developed supraventricular tachycardia, a type of heart rhythm disturbance, due to hypomagnesaemia while using lansoprazole, a common PPI. The patient's arrhythmia resolved after intravenous magnesium replenishment and her serum magnesium remained within reference values after discontinuing the PPI. This case highlights the importance of considering hypomagnesaemia as a potential side effect of long-term PPI use, particularly in patients presenting with unexplained arrhythmias.

A Hidden Oasis in the Desert of Side Effects

This case report serves as a reminder that even widely used and seemingly safe medications can have unexpected side effects. It underscores the need for vigilant monitoring and proactive management, especially in patients on long-term PPI therapy. This research emphasizes the importance of considering hypomagnesaemia as a potential cause of unexplained symptoms, particularly those related to heart rhythm disturbances.

A Desert of Knowledge to Navigate

The study reveals that the desert of medical knowledge is vast and constantly evolving. It highlights the importance of maintaining a critical and inquisitive approach to patient care, remaining aware of potential side effects, even of commonly used medications. By remaining vigilant and proactive, healthcare providers can better identify and manage unexpected complications, ensuring the safety and well-being of their patients.

Dr.Camel's Conclusion

This case report is a valuable reminder that even in the seemingly familiar landscape of commonly used medications, hidden side effects can lurk. It emphasizes the need for healthcare providers to remain vigilant and consider the potential for hypomagnesaemia, especially in patients on long-term PPI therapy who present with unexplained symptoms, particularly those related to heart rhythm disturbances.

Date :
  1. Date Completed 2015-02-21
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

24414180

DOI: Digital Object Identifier

PMC3903331

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・Side Effects of lansoprazole
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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