The retinoid X receptor agonist bexarotene relieves positive symptoms of schizophrenia: a 6-week, randomized, double-blind, placebo-controlled multicenter trial.

Author: BenatovRuben, BushIlan, ElliotHadi, GibelAnatoly, LernerVladimir, MiodownikChanoch, RitsnerMichael S, SirotaPinchas

Paper Details 
Original Abstract of the Article :
The limitations of antipsychotic therapy in schizophrenia and schizoaffective disorder led to the investigation of the putative utility of pharmacologic augmentation strategies. The antitumor agent bexarotene via nuclear retinoid X receptor (RXR) activation might modulate numerous metabolic pathways...See full text at original site
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引用元:
https://doi.org/10.4088/JCP.12m08160

データ提供:米国国立医学図書館(NLM)

Bexarotene: A New Hope for Schizophrenia Treatment?

The world of mental health is a complex and often challenging landscape. Schizophrenia is a serious mental illness that can have a devastating impact on individuals and their families. It's like navigating a desert with a distorted perception of reality, struggling to find a clear path and a stable sense of self. Researchers are constantly seeking new treatments to alleviate the symptoms and improve the quality of life for people with schizophrenia. This study investigates the potential benefits of bexarotene, a drug originally developed for cancer treatment, as an add-on therapy for schizophrenia.

Bexarotene: A Potential Oasis in the Desert of Schizophrenia

This study found that bexarotene, when added to existing antipsychotic treatments, may help to reduce the positive symptoms of schizophrenia. It's like discovering a hidden oasis in the desert, offering a chance for relief and improvement. While the study showed promising results, further research is needed to fully understand the long-term effects and efficacy of bexarotene in treating schizophrenia.

The Quest for New Treatments Continues

This study highlights the ongoing search for better treatments for schizophrenia. It's like continuing to explore the vast desert, seeking out new resources and solutions to improve the lives of those affected by this complex illness. The study underscores the importance of exploring innovative therapies and approaches to address the challenges faced by people with schizophrenia.

Dr. Camel's Conclusion

This study provides a glimpse of hope for those struggling with schizophrenia. Bexarotene, a drug originally developed for cancer treatment, shows promise as a potential add-on therapy for managing the symptoms of schizophrenia. It's like finding a new trail through the desert, leading to a more promising future for those affected by this complex illness.

Date :
  1. Date Completed 2014-04-08
  2. Date Revised 2018-12-03
Further Info :

Pubmed ID

24434091

DOI: Digital Object Identifier

10.4088/JCP.12m08160

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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