The evaluation of analgesic effects of milnacipran and sertraline in tail-flick test.

Author: ErkoseogluI, KadiogluM, KalyoncuN I, KesimM, PepeogluD, YanikM N, YarisE

Paper Details 
Original Abstract of the Article :
Antidepressant drugs are used in the treatment of pain as an adjuvant or alone. It has been shown that antidepressant drugs have analgesic effects in various diseases (diabetic neuropathy, low back pain, cancer pain etc.) Sertraline is a potent serotonin re-uptake inhibitor. Some antidepressant drug...See full text at original site
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引用元:
https://doi.org/10.4149/bll_2014_001

データ提供:米国国立医学図書館(NLM)

Milnacipran and Sertraline: Exploring the Desert of Analgesic Effects

The world of pain management is a vast and complex desert, where researchers seek effective and safe ways to alleviate suffering. This study delves into the analgesic effects of milnacipran and sertraline, two antidepressants commonly used for pain management. It's like a skilled caravan leader, guiding explorers through the intricate pathways of pain relief.

The Quest for Pain Relief

The research, like a meticulous desert expedition, investigates the analgesic effects of milnacipran and sertraline in mice, using the tail-flick test to assess their pain-relieving properties. The findings, like a clear oasis in the desert, suggest that both drugs exhibit analgesic effects, particularly after chronic application. It's as if these medications are potent desert plants, offering relief from the scorching heat of pain.

A Glimpse into Pain Management

This research provides valuable insight into the potential of antidepressant drugs like milnacipran and sertraline for pain management. It suggests that these medications may offer an alternative or complementary approach to pain relief, particularly in cases of chronic pain. Imagine these medications as a soothing balm, alleviating the discomfort and restoring a sense of well-being.

Dr. Camel's Conclusion

This study offers a promising glimpse into the potential of antidepressant drugs for pain management. It highlights the importance of exploring the multifaceted properties of these medications and their potential applications in diverse clinical settings. As a researcher, I am dedicated to unraveling the mysteries of pain and developing more effective and compassionate treatment strategies for those who suffer.

Date :
  1. Date Completed 2014-05-09
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

24471894

DOI: Digital Object Identifier

10.4149/bll_2014_001

Related Literature

SNS
PICO Info
in preparation
Languages

English

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