Clinical and economic evaluation of tapentadol extended release and oxycodone/naloxone extended release in comparison with controlled release oxycodone in musculoskeletal pain.

Author: ColuzziFlaminia, RuggeriMatteo

Paper Details 
Original Abstract of the Article :
Chronic pain is a leading cause of disability and represents a relevant societal burden. Opioids are widely used for managing chronic non-cancer pain; however, the high incidence of side effects is often the main reason for discontinuation. Two formulations have recently been studied to improve the ...See full text at original site
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引用元:
https://doi.org/10.1185/03007995.2014.894501

データ提供:米国国立医学図書館(NLM)

Clinical and Economic Evaluation of Opioids for Musculoskeletal Pain

This research delves into the intricate world of pain management, specifically focusing on the use of opioids for chronic musculoskeletal pain. Imagine a patient, burdened by persistent pain, seeking relief from opioids. This research aims to compare the clinical and economic effectiveness of different opioid formulations.

The study uses a meta-analysis approach to indirectly compare the effectiveness and cost-effectiveness of tapentadol extended release (ER) and oxycodone/naloxone ER with controlled release (CR) oxycodone for treating musculoskeletal pain. The researchers meticulously analyzed data from previous studies to identify the optimal opioid formulation for this condition.

The study's findings are like a compass, guiding clinicians towards the most effective and cost-effective opioid options for managing musculoskeletal pain. While the study suggests that tapentadol ER and oxycodone/naloxone ER might offer comparable pain relief to CR oxycodone, further research is needed to determine the long-term benefits and risks associated with these newer formulations.

Navigating the Opioid Landscape: A Complex Journey

This research highlights the complexities of managing chronic pain with opioids. It emphasizes the need for a balanced approach that considers both clinical effectiveness and cost-effectiveness.

Dr. Camel's Conclusion

This research, like a desert caravan navigating a winding path, highlights the complexities of pain management with opioids. It underscores the need for careful consideration of different opioid formulations, balancing clinical efficacy with cost-effectiveness. It's a reminder that the quest for better pain management is an ongoing journey, requiring a multi-faceted approach and a commitment to improving patient outcomes.

Date :
  1. Date Completed 2015-06-02
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

24528146

DOI: Digital Object Identifier

10.1185/03007995.2014.894501

Related Literature

SNS
PICO Info
in preparation
Languages

English

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