Safety evaluation of substituting clopidogrel for ticlopidine in Japanese patients with ischemic stroke--Hiroshima ticlopidine, clopidogrel safe exchange trial.

Author: AokiShiro, HosomiNaohisa, ItoHijiri, KataokaSatoshi, KohriyamaTatsuo, MatsumotoMasayasu, MiharaChie, MukaiTomoya, NezuTomohisa, NodaKouichi, NomuraEiichi, OhtsukiToshiho, OtaTaisei, TakamatsuKazuhiro, TakedaIkuko, ToriiTsuyoshi, YamadaAtsuo, YokoyamaTakakazu

Paper Details 
Original Abstract of the Article :
Clopidogrel is sometimes substituted for ticlopidine when cerebrovascular or cardiovascular patients develop hematologic abnormalities after ticlopidine treatment. However, the adverse event rate after the substitution to clopidogrel remains undetermined. Therefore, in this study, we aimed to define...See full text at original site
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引用元:
https://doi.org/10.1016/j.jstrokecerebrovasdis.2013.12.025

データ提供:米国国立医学図書館(NLM)

Switching Clopidogrel for Ticlopidine in Stroke Patients

The field of stroke treatment is constantly evolving, and finding the best medications for patients is a top priority. This research delves into the safety of substituting clopidogrel for ticlopidine, a common practice when stroke patients develop blood abnormalities after taking ticlopidine. They used [a clinical trial] to assess the risk of adverse events when switching medications without a washout period. Their findings revealed that substituting clopidogrel for ticlopidine without a washout period might be safe and effective, offering a valuable insight for treating stroke patients.

A Safe and Effective Switch?

The study provides encouraging news for stroke patients who experience blood abnormalities after ticlopidine treatment. The researchers discovered that switching to clopidogrel without a washout period might be a safe and effective approach. This eliminates the need for a pause in treatment, potentially improving patient outcomes.

The Impact on Stroke Patients

This research could lead to more efficient and personalized stroke treatment plans. For patients experiencing side effects from ticlopidine, clopidogrel might offer a viable alternative, potentially preventing further complications. This could significantly improve the quality of life for stroke patients while managing their condition.

Dr.Camel's Conclusion

Switching medications can be a tricky situation, especially for patients with complex conditions like stroke. This study provides crucial information about the safety and effectiveness of switching from ticlopidine to clopidogrel. Like a thirsty camel finding a cool oasis in the desert, this discovery could offer a much-needed solution for stroke patients struggling with medication side effects.

Date :
  1. Date Completed 2015-02-23
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

24560246

DOI: Digital Object Identifier

10.1016/j.jstrokecerebrovasdis.2013.12.025

Related Literature

SNS
PICO Info
in preparation
Languages

English

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