Paediatric palliative care: intravenous methylnaltrexone relieves constipation.

Author: ChohanOsman, MayerAnton, YeomansonDaniel

Paper Details 
Original Abstract of the Article :
Methylnaltrexone, a peripheral opioid μ-receptor antagonist is licensed for subcutaneous administration for the treatment of severe opioid-induced constipation in adults. We describe the use of intravenous methylnaltrexone in a 3-year-old boy receiving a subcutaneous diamorphine infusion for palliat...See full text at original site
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引用元:
https://doi.org/10.1136/bmjspcare-2012-000291

データ提供:米国国立医学図書館(NLM)

Intravenous Methylnaltrexone: A Promising Treatment for Opioid-Induced Constipation in Pediatric Palliative Care

The [management of opioid-induced constipation (OIC)] in pediatric palliative care presents unique challenges. This case report describes the successful use of intravenous methylnaltrexone, a peripheral opioid μ-receptor antagonist, to relieve OIC in a three-year-old boy receiving subcutaneous diamorphine for palliative care. The authors highlight the potential benefits of intravenous methylnaltrexone as a valuable addition to the treatment options available for OIC in children receiving palliative care. Imagine a thirsty traveler in a desolate desert, with intravenous methylnaltrexone acting as a refreshing oasis, providing relief from the discomfort of OIC.

Intravenous Methylnaltrexone: A Rapid and Effective Solution

The case report demonstrates the rapid and effective relief provided by intravenous methylnaltrexone. The patient's constipation, which had persisted for three weeks despite conventional laxatives, was resolved within minutes of the injection. Moreover, the authors report no adverse effects associated with the intravenous administration of methylnaltrexone. This suggests that intravenous methylnaltrexone could be a safe and effective option for managing OIC in children requiring palliative care.

Expanding Treatment Options: Improving Pediatric Palliative Care

This case report provides valuable insights into the potential benefits of intravenous methylnaltrexone in pediatric palliative care. The authors highlight the importance of expanding treatment options for OIC in this vulnerable population. By providing relief from OIC, healthcare providers can improve the overall well-being and comfort of children receiving palliative care. Remember, even in the most challenging of circumstances, there is always hope for finding solutions and improving the lives of those in need.

Dr.Camel's Conclusion

This case report demonstrates the effectiveness of intravenous methylnaltrexone in relieving opioid-induced constipation in a pediatric palliative care setting. The rapid and sustained relief achieved, coupled with the absence of adverse effects, suggests that intravenous methylnaltrexone could be a valuable addition to the treatment options for OIC in this population.

Date :
  1. Date Completed 2015-06-02
  2. Date Revised 2016-11-25
Further Info :

Pubmed ID

24644335

DOI: Digital Object Identifier

10.1136/bmjspcare-2012-000291

Related Literature

SNS
PICO Info
in preparation
Languages

English

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