Dextromethorphan/quinidine for the treatment of pseudobulbar affect.

Author: CasselmanJessica, PatatanianEdna

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To evaluate the role of dextromethorphan/quinidine (DM/Q; Nuedexta™) in the treatment of pseudobulbar affect (PBA). DATA SOURCES: A literature search of MEDLINE/PubMed (January 1966-June 2013) was conducted using search terms pseudobulbar affect, pathological laughing and/or crying, emot...See full text at original site
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引用元:
https://doi.org/10.4140/TCP.n.2014.264

データ提供:米国国立医学図書館(NLM)

Dextromethorphan/Quinidine: A Potential Oasis in the Desert of Pseudobulbar Affect

The [neurology] field is constantly seeking new ways to manage [pseudobulbar affect] (PBA), a disorder characterized by involuntary crying and laughing. This research investigates the potential therapeutic role of [dextromethorphan/quinidine] (DM/Q) in treating PBA. The study reviews existing literature on DM/Q's safety and efficacy in PBA, analyzing clinical trials and case reports.

The Effectiveness of DM/Q: A Glimpse into a Potential Solution

The study's review suggests that DM/Q may be a viable short-term treatment option for PBA. Although the available evidence is limited by small sample sizes and short treatment durations, several clinical trials have shown positive outcomes with DM/Q. The desert of PBA can be a lonely and isolating place, and finding effective treatments is crucial for improving quality of life. DM/Q offers a potential oasis of relief for those struggling with PBA.

The Need for Further Research: Navigating the Desert of Uncertainty

The limited evidence base necessitates further research to fully understand the long-term safety and efficacy of DM/Q in treating PBA. Larger, longer-term clinical trials are needed to provide more robust evidence. The desert of PBA is filled with uncertainty, and finding reliable and effective treatments requires a commitment to ongoing research and exploration.

Dr.Camel's Conclusion

The available evidence suggests that DM/Q may offer a potential treatment option for PBA, but further research is needed to confirm its long-term safety and efficacy. The desert of PBA is a challenging landscape to navigate, but with continued research and a dedication to finding effective therapies, we can create oases of hope and relief for those affected by this debilitating condition.

Date :
  1. Date Completed 2014-11-24
  2. Date Revised 2023-12-13
Further Info :

Pubmed ID

24704895

DOI: Digital Object Identifier

10.4140/TCP.n.2014.264

Related Literature

SNS
PICO Info
in preparation
Languages

English

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