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Efficacy and safety of telaprevir (TVR) triple therapy in a 'real-life' cohort of 102 patients with HCV genotype 1: interim analysis after 24 weeks of treatment.
Author: BergC P, EgetemeyrD P, FranzC, Janke-MaierP, LauerU M, MalekN P, WernerC R
Original Abstract of the Article :
Since 2011, telaprevir (TVR)-based triple therapy is the new treatment standard for hepatitis C genotype 1 virus infection. The aim of our retrospective interim analysis encompassing the first 24 weeks on TVR-based triple therapy was to assess 'real-life' antiviral efficacy and side effects in a lar...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元：
https://doi.org/10.1111/jvh.12145
データ提供：米国国立医学図書館（NLM）
A Real-World Look at Telaprevir Therapy: Navigating the Challenges of Hepatitis C Treatment
Hepatitis C, a viral infection that affects the liver, poses a significant health challenge worldwide. This study, like a camel navigating a treacherous desert landscape, explores the efficacy and safety of telaprevir (TVR)-based triple therapy for hepatitis C genotype 1 virus infection in a 'real-life' cohort of patients.
A Real-World Perspective: Telaprevir Therapy in Practice
The study provides a real-world perspective on the effectiveness of TVR-based triple therapy, comparing its performance in clinical practice to the results of large-scale clinical trials. The findings, as clear as a desert sky at night, reveal comparable antiviral effects in a 'real-life' setting. However, the study also highlights the frequent occurrence of side effects, requiring multiple therapeutic interventions. The researchers provide a realistic assessment of the challenges and complexities of treating hepatitis C in clinical practice.
Navigating the Risks and Benefits: A Balanced Approach to Hepatitis C Treatment
This study, like a well-placed oasis, provides valuable insights into the real-world application of TVR-based triple therapy. The research highlights both the potential benefits and challenges of this treatment approach, providing a balanced perspective for patients and clinicians. The findings underscore the importance of careful monitoring and management of side effects to optimize treatment outcomes for individuals with hepatitis C.
Dr.Camel's Conclusion
This study offers a realistic assessment of the challenges and complexities of treating hepatitis C in the 'real-world' setting. The research highlights the importance of carefully weighing the potential benefits and risks of treatment options, such as TVR-based triple therapy, to ensure optimal outcomes for individuals with this challenging condition.
Date :
- Date Completed 2014-11-24
- Date Revised 2014-04-10
Further Info :
Related Literature
English
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