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Effects of milnacipran on neurocognition, pain, and fatigue in fibromyalgia: a 13-week, randomized, placebo-controlled, crossover trial.
Author: KeefeRichard S, KimJeong Lan, MarksDavid M, MasandPrakash S, MilletRobert A, PatkarAshwin A, ReleShilpa, YerramsettyPallavi
Original Abstract of the Article :
OBJECTIVE: To investigate whether milnacipran is safe and effective in improving cognitive function in patients with fibromyalgia. METHOD: Patients were randomly assigned to receive milnacipran or placebo for 6 weeks, followed by a 1-week washout and then crossover to the other arm for another 6 we...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977772/
データ提供:米国国立医学図書館(NLM)
Milnacipran for Fibromyalgia: A Desert Oasis of Potential?
Fibromyalgia, a chronic pain condition characterized by widespread musculoskeletal pain, fatigue, and cognitive dysfunction, is often difficult to treat. This study, published in Journal of Pain Research, investigates the effects of milnacipran, a serotonin-norepinephrine reuptake inhibitor, on cognitive function, pain, and fatigue in patients with fibromyalgia. The researchers conducted a randomized, placebo-controlled, crossover trial, finding that milnacipran may have a potential role in improving pain, disability, and mood, but its effects on cognition remain uncertain.
Milnacipran for Fibromyalgia: A Complex Landscape
The study highlights the complex nature of fibromyalgia and the need for effective treatments that address the multifaceted symptoms. While milnacipran showed promise in reducing pain, disability, and mood symptoms, its impact on cognition was less clear. This underscores the need for further research to better understand the role of milnacipran and other medications in managing the cognitive challenges associated with fibromyalgia. It's like navigating a vast desert with multiple paths, where the optimal route for each individual may vary.
Milnacipran for Fibromyalgia: What to Consider?
This study suggests that milnacipran may offer some benefits for patients with fibromyalgia, but its impact on cognition requires further investigation. It's a reminder that the search for effective treatments for chronic pain conditions is ongoing. As researchers continue to explore new avenues, patients and clinicians can work together to find the most appropriate treatment strategies for managing the complex symptoms of fibromyalgia.
Dr.Camel's Conclusion
This study offers a glimpse into the potential of milnacipran for managing fibromyalgia, highlighting its potential benefits in reducing pain, disability, and mood symptoms. However, the study also underscores the need for further research to fully understand the effects of milnacipran on cognition. It's a reminder that the journey to finding effective treatments for chronic pain conditions is a continuous exploration, requiring ongoing research and collaboration.
Date :
- Date Completed 2014-05-06
- Date Revised 2021-10-21
Further Info :
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